Question

Which base location in the figure below is LEAST discriminating in the bases that it can pair with as described by the wobble
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Answer #1

Solution

The answer is option b i.e. "A"

Wobble hypothesis was proposed by Francis Crick in 1966.

According to the wobble hypothesis there is a a base pair at third position which is known to be in relaxed state. This base pair helps tRNA to recognize multiple codons.

"A" is the wobble position is unable to discriminate and ensure pairing.

The option a, c and d are wrong because they discriminate bases and pair with the described pattern of wobble hypothesis.

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