Question 1
Answer is option(d) has high transferrin saturation
It is a genetic disease in which intestinal absorption of iron increases and as a result, Total body iron stores are increased.
Transferrin is an iron binding protein. Excess of iron in the body leads to higher saturation of transferrin in the blood.
**Hepcidin levels are low in hereditary hemochromatosis.
Question 2
Answer is option (a) paroxysmal nocturnal hemoglobinuria
PNH is a condition in which RBC gets destroyed by our own innate immune system.
It is due to inability to attach protein requiring GOI link to CD55 membrane proteins.
Question 3
Answer is option (c) Increased intravascular hemolysis
Haptoglobin is a protein produced by liver which is used to clear free haemoglobin found outside the red cells.
When there is increased intravascular hemolysis, there will be large amount of free hemoglobin in the blood. This will cause depletion of haptoglobin.
thanks Which is true regarding a patient with hereditary hemochromatosis? Has high hepcidin activity Has low...