Question

The most common mutation occuring in people with cystic fibrosis is the loss of a single amino acid (phenylalanine) at position 508 of the protein. This mutation O a. is a point mutation b. is an single nucleotide polymorphism c. is a deletion of 3 nucleotides d. in an insertion of a single nucleotide e. is a chromosomal rearrangement → Moving to another question will save this response. In Concience in 5 min you. For ence ne

Answer 1

Ans:- c) is a deletion of 3 nucleotide.

concept:- 1Amino acid is coded by a set of 3 neuleotide.

so for change of only one amino acid there must be a deletion of 3 neuleotide.

option b ) is wrong because single nucleotide polymorphisms if only single nucleotide is changed then new aminoacid will be formed . There will be no loss of amino acid as mentioned in que.

Option a) is also similar to option b)

D) insertion of single neuleotide will change the sequence of all the amino acids in the protein chain. Because triplets are read in a sequence.