Question

One of the most difficult aspects of signaling through pathways that involve proteolysis is keeping track...

One of the most difficult aspects of signaling through pathways that involve proteolysis is keeping track of the names of the components and their functions. Sort the following list of proteins into the Notch, Wnt/B-cetenin, and Hedgehog signaling pathways, list them in he order they function, and select one or more appropriate descriptors that identify their role.

Protein

A. B-catenin

B. Cubitus interruptus )Ci)

C. Delta

D. Dishevelled

E. Frizzled

F. Glycogen sythase kinase 3 (GSK3)

G. Hedgehog

H. iHog

I. LRP

J. Notch

K. Patched

L. Presenilin

M. Smoothened

N. Rbpsuh

O. Wnt

Function (Type of protein)

1. Amplifier

2. Anchoring

3. Extracellular signal

4. Gene regulatory

5. Integrator

6. Latent gene regulator

7. Modulator

8. Protease

9. Receptor

10. Relay

11. Scaffold

12. Transducer

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Answer #1

Notch

C. Delta

D. Dishevelled

F. Glycogen sythase kinase 3 (GSK3)

J. Notch

N. Rbpsuh

Wnt/B-catenin

A. B-catenin

E. Frizzled

I. LRP

L. Presenilin

O. Wnt

Hedgehog

B. Cubitus interruptus )Ci)

G. Hedgehog

H. iHog

K. Patched

M. Smoothened

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