the synthesis of what deoxyribonucleotide will be directly affected by inhibition of dhfr
the synthesis of what deoxyribonucleotide will be directly affected by inhibition of dhfr
Homework Answers
A dihydrofolate reductase inhibitor (DHFR inhibitor) is a molecule that inhibits the function of dihydrofolate reductase, and is a type of antifolate.
Since folate is needed by rapidly dividing cells to make thymine, this effect may be used to therapeutic advantage. For example, methotrexate is used as cancer chemotherapy because it can prevent neoplastic cells from dividing.[1][2] Bacteria also need DHFR to grow and multiply and hence inhibitors selective for bacterial vs. host DHFR have found application as antibacterial agents.
Tetrahydrofolate synthesis pathway
Classes of small-molecules employed as inhibitors of dihydrofolate reductase include diaminoquinazoline and diaminopyrroloquinazoline,diaminopyrimidine, diaminopteridine and diaminotriazines.
Add Answer to:
the synthesis of what deoxyribonucleotide will be
directly affected by inhibition of dhfr
Of the six categories of inhibition, (inhibition of cell wall synthesis, inhibition of protein synthesis, disruption...
Of the six categories of inhibition, (inhibition of cell wall synthesis, inhibition of protein synthesis, disruption of cytoplasmic membrane, inhibition of general metabolic pathway, inhibition of DNA or RNA synthesis, or inhibition of pathogens attachment or entry into host cell) which would be effective against viruses? Which would be practical to use?
here are the possible choices for the questions: Inhibition of cell wall synthesis. Inhibition of nucleic...
here are the possible choices for the questions: Inhibition of cell wall synthesis. Inhibition of nucleic acid synthesis. Inhibition of protein synthesis. Inhibition of synthesis of essential metabolites. Injury to the plasma membrane. Here are the Questions: Which of the following best describes the mode of action of Penicillin? Which of the following best describes the mode of action of Sulfamethoxazole (a sulfa drug)? Which of the following best describes the mode of action of Tetracycline?
All of the following methods of actions are bacteriostatic except: competitive inhibition with folic acid synthesis...
All of the following methods of actions are bacteriostatic except: competitive inhibition with folic acid synthesis inhibition of protein synthesis inhibition of cell wall synthesis competitive inhibition with DNA gyrase
Which of the following modes of action would not be fungicidal? a. inhibition of peptidoglycan synthesis...
Which of the following modes of action would not be fungicidal? a. inhibition of peptidoglycan synthesis b. inhibition of mitosis c. injury to the plasma membrane d. inhibition of nucleic acid synthesis e. All of the above are fungicidal modes of action
what hormones are directly affected by hypopituitarism and what effect does it have on the rest of the endocrine system...
what hormones are directly affected by hypopituitarism and what effect does it have on the rest of the endocrine system?
b. Uncompetitive inhibition. c. Mixed inhibition. d. Pure noncompetitive inhibition. 22. What type of inhibition is...
b. Uncompetitive inhibition. c. Mixed inhibition. d. Pure noncompetitive inhibition. 22. What type of inhibition is the Lineweaver-Burk plot? 1/yo a. Competitive inhibition. b. Uncompetitive inhibition. c. Mixed inhibition. d. Pure noncompetitive inhibition. 23. In the Question 22, how do the values of [I] change in the 1/[S] arrow's direction? a. Increasing. b. Decreasing c. Increasing or decreasing. d. Do not change 24. Which of the following inhibition types cause ESI? n Competitiye, uncompetitive, and mixed inhibition
If a restaurant buys tomatoes for $1,000 then GDP is not directly affected If a restaurant...
If a restaurant buys tomatoes for $1,000 then GDP is not directly affected If a restaurant buys forks and knives for $1,000 then Investment spendingcreas (Select) Investment spending increases GDP is not directly affected • Previous Consumption spending increases
1: Areas that are directly affected by expanding the human population are known as what? Options:...
1: Areas that are directly affected by expanding the human population are known as what? Options: Hot spots, Extirpated areas, Threatened areas, Endangered areas Fill in the Blanks Questions: 2: _____________ is the greatest threat to biodiversity today. 3: The variety of different DNA is known as ______________________ diversity. 4: _______________means that a species is likely to become endangered soon.
In aquatic systems, which abiotic and biotic characteristics are most directly affected by depth? Which are...
In aquatic systems, which abiotic and biotic characteristics are most directly affected by depth? Which are the least affected? This is for an ecology class. Please elaborate. Thanks!
12. For the purification of DHFR experiment, the protein was eluted with 0.300 M imidazole. the...
12. For the purification of DHFR experiment, the protein was eluted with 0.300 M imidazole. the elution fractions that were dialyzed equaled 3.00 ml. The dialysis bag was placed in 500.0 mL of dialysis buffer that contained no imidazole. Assume a total volume of 503.00 mL and the solution reach equilibrium. What is the equilibrium concentration of imidazole in the sample?
All of the following methods of actions are bacteriostatic except: competitive inhibition with folic acid synthesis inhibition of protein synthesis inhibition of cell wall synthesis competitive inhibition with DNA gyrase
b. Uncompetitive inhibition. c. Mixed inhibition. d. Pure noncompetitive inhibition. 22. What type of inhibition is the Lineweaver-Burk plot? 1/yo a. Competitive inhibition. b. Uncompetitive inhibition. c. Mixed inhibition. d. Pure noncompetitive inhibition. 23. In the Question 22, how do the values of [I] change in the 1/[S] arrow's direction? a. Increasing. b. Decreasing c. Increasing or decreasing. d. Do not change 24. Which of the following inhibition types cause ESI? n Competitiye, uncompetitive, and mixed inhibition
If a restaurant buys tomatoes for $1,000 then GDP is not directly affected If a restaurant buys forks and knives for $1,000 then Investment spendingcreas (Select) Investment spending increases GDP is not directly affected • Previous Consumption spending increases
12. For the purification of DHFR experiment, the protein was eluted with 0.300 M imidazole. the elution fractions that were dialyzed equaled 3.00 ml. The dialysis bag was placed in 500.0 mL of dialysis buffer that contained no imidazole. Assume a total volume of 503.00 mL and the solution reach equilibrium. What is the equilibrium concentration of imidazole in the sample?
Most questions answered within 3 hours.
-
The diagram below shows a meter shunted by a parallel resistance
Rs. The maximum value for...
asked 3 minutes ago -
Explain some of the pros and cons of converting a C Corporation
into an S Corp?...
asked 2 minutes ago -
Be sure to answer all parts. A solution contains 0.107 mol of
NaCl dissolved in 9.35...
asked 2 minutes ago -
1. An 25.96 g sample of aluminum is placed on a 45.15 g sample
of copper...
asked 12 minutes ago -
Calculate the mass of p-dichlorobenzene (mm=147.00 g/mol) that
when dissolved in 125 ml cyclohexane (d=0.779 g/mol,...
asked 20 minutes ago -
An infinitely long solid conducting cylindrical shell of radius
a = 3.8 cm and negligible thickness...
asked 18 minutes ago -
A defibrillator is used during a heart attack to restore the
heart to its normal beating...
asked 24 minutes ago -
Describe how humans have affected the numerous pathways and
reservoirs in the carbon cycle that have...
asked 25 minutes ago -
Which of the following statements is true of a distribution
rollover (not a trustee-to-trustee transfer) from...
asked 27 minutes ago -
Matching: What are 4 fundamental activities in software
processes?
definition of the software function and operational...
asked 33 minutes ago -
University Printers has two service departments (Maintenance and
Personnel) and two operating departments (Printing and Developing)....
asked 48 minutes ago -
This journal deals with globalization and its economic effects.
US firms have almost no restrictions on...
asked 47 minutes ago