which or the following reactions show the incorrect enolate formation?
which or the following reactions show the incorrect enolate formation? NaOEt RT 0 NaOEt RT O...
MULTIPLE CHOICE A NaOET ii RT B Oө NaOEt RT с LDA -78°C D NaOEt RT E All are correct Zoom Which of the following reactions show the incorrect enolate formation? A А B B
4. Draw the products of the following sequences of reactions. 1) NaOET, HOE 1) NaOEt Eto OEt 2) H3O+ 2) Br | 1) LDA, -78°C 2) 0 H30+ heat H 3) NaOH, heat 1) LDA (1.1 equiv), -78°C, THE 2) CH3Br 1) CH3CH2MgBr 2) H30* H2, Pd-C LU H2SO4 NaOH, H2O 1) LDA, -78°C 2) HOE 3) H30+ 1) O3 2) CH2SCH3
Please predict the major products of the following reactions and rationalize your answers OLI CH3 PACHO H307 CH3 OLI CH3 PACHO Hac^ CH One approach to the synthesis of Z-enolate is using a boron reagent. Please predict the major product of the following reaction and rationalize your answer R BOTT OBR2 PhCHO VR Pr2NET R -78 °C Z-enolate Please rationalize the following transformation 9 OH O OH LDA FIO ETO CHO E-enolate formation anti 90-93% syn 7-10%
le chatelier experimen Thursday). 1. What starting material and reagents are needed for the following multi-step synthesis (HINT: aldol reactions work best when the starting material can only form one enolate)? 5 он о D. NaOH, H2O, Heat F. HO E. NaOH, H2O G. LDA Starting Material: Reagents: 2. LDA is a strong, sterically hindered base and will form the enolate. Sodium hydride is a weak base and will form the _ - enolate. Kinetic enolates are the stable and...
Which of the following bases works best to quantitatively convert ethyl acetate to its enolate? base OEt OEI a) NaOET b) NaOH c) CHLI d) LDA Which has the highest percentage of enol in a keto-enol equilibrium?
Select the major product of the following reaction scheme: Reaction CH3 H3C OH LDA NaOET CrO2, H2SO4 Acetone, 0 °C THF -78 °C -78 °C to EtOH, 78 °C 25 °C НО. B E F OH (No Reaction) ol. A o II. B ollc IV.D OV. E OVI.F
1. Draw a mechanism for the following Aldol condensation reaction under basic conditions, including the formation of the enolate. Please include ALL lone pair electrons, formal charges, and stereo/regiochemistry whenever applicable. 1) LDA, H2O 2) LAH 2. Draw a mechanism for the following Dieckmann reaction under basic conditions, including the formation of the enolate. Please include ALL lone pair electrons, formal charges, and stereo/regiochemistry whenever applicable. 1) NaOEt 2) Hзо* OEt 3. Draw a mechanism for the following alkylation reaction...
Question 6 (9 marks) Give the products of the following reactions (do not supply mechanisms, just give the product structure) NaNH2 a. H3C = H + LDA -78 °C olive O NaOet — + NaOEt OEt (3+3+3 marks)
Provide the major product(s) for the following Provide the major product(s) for the following reactions. Be sure to note stereochemistry and racemic mixtures. NaOH, H29 2 100 °Ç ? NaOH, H2O H 0°C H W H CCl3 OC (provide product of both steps) H a. Hn b. CHEM 370 W13 Homework Page 1 of 2 giorel Noot Hoi solu NOEL IN DER NaOH, H2O 100 °C Hv NaOET, H OEt EtOH 8. Eto- i. LDA, -78°C NaO Me MeOH Оме...
Which sequence of conditions best accomplishes the transformation below? OH OH steps Select one: O a. i) LDA, -78 °C; ii) CH3CH2CHO; iii) Zn, HCI o b.i) NaOEt -78 °C; ii) CH3CH2CHO; iii) Zn, HCI O c. 1) LDA, -78 °C; ii) CH3CH2CHO; iii) NaBHA o d. i) NaOet 25 °C; ii) CH3CH2CHO;iii) NaBH4