4. Draw the products of the following sequences of reactions. 1) NaOET, HOE 1) NaOEt Eto...
Мар сар reagents and conditions necessary to efficiently carry out the following muti-skom NaOH, acetone rom the starting material on the left to the product on the right. Do not worry a 1. LDA, THF, -78 C, 2. NaOH, H20, heat PPh3, n-Buli 1. ethyl acetoacetate, 2. NaoÉt, HOE 1. NaOET, HOEt, methyl vinyl ketone H2, Pd-C (one equiv.) Mapa Show any steps, reagents and conditions necessary to efficiently carry out the following muti-step transformations from the sta NaOH, acetone...
4. Predict the Product: NaBHA MeOH 1. LAH 요 2. H30* Ph3P li Php NaOEt EtOH 1. TBS-CI, imidazole ОН ОН 2. HO TsOH 1. NaOET 2. Br Br 3. NaOET 1. (1.1 equiv) LDA THF, -78°C 2. Br 1. (0.9 equiv) LDA THF, 0°C 2. Br
1) Reactions. Provide the major product for each reaction sequence, account for stereochemistry 1) PCC, CHCI 2) Bry, acetic acid 3) KOBU, A 4) NaOEI, ETOH, P CO- 5) H30 workup 6) THF, H.COPPA HC CH2 O e .cat. Pd(OAc) cat. PPh. DMF, EIN 2) LDA, THF. -78 °C 3) Chichen H3O* workup 4) NaBH, EtOH, then H3O+ workup 5) cat. TSOH, benzaldehyde (c) L AL SUO TESTE TO 1) cat. H2SO4. A лон 2) O3, CH, Cl, then (CH),...
3. (3x10-30 points) Reactions. Give the product structure of following reactions, indicate stereochemistry where appropriate. A) + Ph2pt-CHCH3 i. EtMgBr (excess) B) . H3o i. NaOEt Eto C) ii. H,O i. LDA D) i. C2Hs C12, hv E) Me AlC F) NaOEt OEt Ni, H2 H) heat OEt NaOEt EtO OEt Br
give mechanism 3.1 sc)o 2. CH3(CH)&B \ 3. Нзо", heat O/ d) 1. NaOEt 2. dil. H3O OEt 1. LDA, -78°C 2. CH CH2Br f) 1. NaOH, 2 2. H30 1. NaOH, heat g) xs NH3 (SN2) 1. Br2, PBr3 2. H20 h)
Which of the compounds shown below would be the major organic product of the set of reactions shown? 0 Eto V 1) NaOEt 0 2) Br OEt 3) H3O+/A. Но HO Eto Eto C
le chatelier experimen Thursday). 1. What starting material and reagents are needed for the following multi-step synthesis (HINT: aldol reactions work best when the starting material can only form one enolate)? 5 он о D. NaOH, H2O, Heat F. HO E. NaOH, H2O G. LDA Starting Material: Reagents: 2. LDA is a strong, sterically hindered base and will form the enolate. Sodium hydride is a weak base and will form the _ - enolate. Kinetic enolates are the stable and...
Need Help. Will Rate If Complete. NaOH, H20 wborn Bonaparte 1) NaOPr, ProH 2) H30+ OMe 1) NaoMe, MeOH Ome 2) H30+ 1) LDA (1.1 eq) 2) Et 3) H20 1) NaOEt, EtOH 2) H30 Eto OEt COOEt COOEt 1) NaOet, EtOH 2) H2O
1. Predict the major product for the reactions shown below; pick any 5: HO xs CHal Ag20 NaOEt EtOH, Δ -H2O HO но он 0 он H2SO4 H20, A heat 1) PhMgBr 1) NaOH, Br2 2) 5% HCI 2)H3O+, Δ OEt 1) PPh3 3) KOtBu 2) O 1) NaOH on. Br 2) O o 1. Predict the major product for the reactions shown below; pick any 5: HO xs CHal Ag20 NaOEt EtOH, Δ -H2O HO но он 0 он...
Q1- Fill in the boxes with the product of the following reactions. Draw only the PREDOMİNANT REGIOISOMER. When a racemic mixture is formed mark the chiral center with an ASTERICK () and write RACEMİC in the box. 1 Eq LDA 0 1 Eq NaOH 1) 0.5 Eq LDA1) Cat NaOH 2) H30 јнзо-, Heat , NaOEt, EtOH 1. NaOEt EtOH Br 1) NaOH, H2O 2) H3O 3) Heat 1) (CH3)zMgBr 2) H30 2 a2- Fill in the boxes with the...