Question

Answer the following questions. CARBENICILLIN n o For IV. use Add 5mL of rebra nalgo 800mg Sable for 48 hours in the refrigerator EXPIRES 09/09/109 CAUTION: Federal law pros dispersing without The physician's order reads: Carbenicillin G 750 mg IV 6h How many mLs are required for one dose? Why is the concentration 500 mg/mL instead of 526.3 mg/mL ? KEFZOL Add 2.5mL of sterile water for a final concentration of 330mg/ml Stable for 24 hours at room temperature or 7 days in the refrigerator For IV. use 1000mg Read accompanying arouler CAUTION: Federal law prohibis dispensing without prescription EXPIRES 09/09/09 The physician's order reads: Ketzol 165 mg IV 98h How many mLs are required for one dose?

Health and Science Mathamatics class

Answer 1

Answer:

Question 1

1 vial of Injection CARBENICILLIN contain 5 gram = 5000 mg

Add 9.5 ml sterile water in above injection for a final concentration of 500 mg/ ml

So 5000 mg (1 vial) = 10 ml solution after dilution

that means 10ml - 9.5 ml sterile water = 0.5 ml of IV CARBENICILLIN concentrated solution contain 5 gram.

Now physician order : 750 mg IV hourly

1 dose = 750 mg of injection CARBENICILLIN

Coz final concentration of injection CARBENICILLIN contain 500 mg = 1 ml

Therefore, 750 mg = 1/500 X 750 ml = 1.5 ml

1.5 ml solution are required per dose.

Most of IV injection preparation commercially available in the active drug form either solution or suspension. Here we add 9.5 ml of sterile water to final concentration 500mg/ ml that means active drug form in liquid solution of 0.5 ml per vial. That's why concentration 500mg/ ml instead of 526.3 mg/ml.

Answer of question no 2

Here injection KEFZOL 1 vial = 1000 mg

Adding 2.5 ml of sterile water to final concentration of 330 mg / ml

330 mg of injection KEFZOL = 1 ml solution

So 1000 mg of injection KEFZOL ( 1 vial) = 1/ 330x 100 = 3 ml total solution

That means 0.5 ml of injection KEFZOL of active drug in the form of solution

Now physician order : 165 mg IV 8 hourly

Here 330 mg = 1 ml solution of injection KEFZOL

So , 165 mg = 1/340x 165 = 0.5 ml of final concentration of injection KEFZOL

Therefore, 0.5 ml solution of injection KEFZOL required per dose.

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