Question

1. β1- and β2-adrenoceptors _______ while α2-receptors _______.

a. Stimulate adenylyl cyclase and cAMP; enhance Ca²⁺ levels
b. Inhibit adenylyl cyclase and cAMP; stimulate adenylyl cyclase and cAMP
c. Stimulate adenylyl cyclase and cAMP; inhibit adenylyl cyclase and cAMP
d. Increase K+ channel opening; inhibit adenylyl cyclase and cAMP
e. Decrease K+ channel opening; stimulate adenylyl cyclase and cAMP

2. Which of the following can cause dopamine release from the presynaptic terminal?

a. Amphetamines
b. MDMA
c. Cocaine
d. Both a and b, but not c
​e. All of the above

3. In a dose response curve, the absolute amount of drug required to produce an effect is defined to as?

a. Affinity
b. Efficacy
c. Potency
d. Both a and b, but not c
​e. All of the above

Answer 1

1. The correct answer is Option C. β1- and β2-adrenoceptors stimulate adenylyl cyclase and cAMP, while α2-receptors inhibit adenylyl cyclase and cAMP.
2. The correct answer is Option C. Cocaine can cause dopamine release from the presynaptic terminal.
3. The correct answer is Option B. In a dose response curve, the absolute amount of drug required to produce an effect is defined as efficacy.