Question

6) Whale insulin could be distinguished seralogically from pig insulin in spite of identical primary sequence. This is because: A) They were folded at different temperatures in the different species. B) They were folded using different chaperone proteins. C) They were folded as larger precursor proteins with differing primary structure D) The antibodies used were made from denatured insulin 7) Enzymes are potent catalysts because they A) increase the equilibrium constants for the reactions they catalyze B) lower the activation energy for the reactions they catalyze. C) are consumed in the reactions they catalyze. D) can prevent the conversion of products back to substrates 8) The role of Asp in the catalytic triad of serine proteases is to: A) reduce the pk, of His and to keep His protonated so that it has a proton to donate to the amide nitrogen of the peptide bond to be hydrolyzed. B) make the catalytic site more acidic so that protons are available to His. C) To make a salt bridge with the N-terminus - leading to the formation of the specificity pocket and reducing the Ku. D) increase the pk, of His so that it will be more attracted to the proton from Ser and to keep the His in a tautomeric form with electrons available for receiving a proton. 9) Which of the following is true for a competitive inhibitor? A) it lowers keat B) it lowers the KM C) it reduces Vmax D) it raises the substrate concentration required for the rate to be 1/2 of Vmax E) it lowers the substrate concentration required for the rate to be 1/2 of Vmax 10) The number of substrate molecules converted to product in a given unit of time by a single enzyme molecule at saturation is referred to as the: A) Michaelis-Menten constant Ku. B) dissociation constant ko. C) turnover number. D) velocity E) maximum velocity Vmax.

Answer 1

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