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explain why it is difficult to have a screening test that has 100% sensitivity and specificity....

explain why it is difficult to have a screening test that has 100% sensitivity and specificity. use labeled drawings as appropirate.

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The sensitivity and specificity of a quantitative tests are dependent on the cut-off value above or below which the test is positive.,for which it is possible but difficult to intetpret in screening test with 100% sensitivity and specificity.In general the higher the sensitivity,the lower the specificity and vice versa.Positive and negative predictive values are useful when considering the value of a test to a clinician.They are dependent on the prevalence of the disease in the population of interest.

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