1. Draw the structure of the following tripeptide as it would exist at physiological pH. Be...
Draw the tripeptide gly-lys-glu as it exists under physiological pH. Write the reaction for the hydrolysis of this tripeptide into the individual amino acids. Be sure to show the reaction conditions and the final products that result under these conditions.
Draw the peptide below (full chemical structure), as it would exist at pH=7. Indicate all bonds (those to hydrogen are optional; you could use 'stick figures' or write methylene as CH, rather than H-C-H). You do not need to indicate stereochemistry, but make sure it is correct if you do. Val- Lys-Mer-TYR-G1v-ser Hd 2 3 equivalents of base
a) Draw the structure of a Gln-Lys-Met tripeptide at pH 7. b) Calculate the pl of the peptide. Show your work.
8:20 PM Draw the structure of the peptide abbreviated PARTY as it would exist at physiological pH Calculate the isoelectric point for this peptide. (Use pK values from Table 4-1.) 4.
true or false. at physiological PH, nearly all amino acids have overall positive charge True False 1) At physiological pH, nearly all amino acids have an overall positive charge. 2) The dipeptide abbreviated as Gly-Lys is the same as the dipeptide abbreviated as Lys-Gly. tide 3) The peptide sequence Gly-Gly-Gly gives the primary structure of a tripeptide. 4) The u-helix is a secondary structure. 5) The triple helix of collagen is a tertiary structure.
1. which tripeptide will most likely line the opening of a Cl- channel? a. His-Lys-Arg b. Gly-Pro-Arg c. Asp-Trp-Tyr d. Asp-Ala-Glu e. Leu-Val-Phe 2. Which tripeptide will most likely line the opening of a K+ channel? (consider side chains at physiological pH) a. His-Lys-Arg b. Gly-Pro-Arg c. Asp-Trp-Tyr d. Asp-Ala-Glu e. Leu-Val-Phe
Click the "draw structure" button to launch the drawing utility. Draw the following peptide at physiological pH. Lys-trp-pro edit structure ... Н н Н Н H3N C N- C -N- C co O C I IZ
B. Write the structures of the following peptides as they would exist at pH=7. Be sure to correctly indicate stereochemistry. TED (note: these are 1-letter codes) S-Arginyl-R-Tyrosine (dipeptide: L-Arg-D-Tyr)
In the box below, draw the structure of the tripeptide Gly-His-Cys as it would appear at pH 7.0.
5. D-sorbital is found in 'sugar-free' chewing gum. It is formed by reducing D-glucose with NaBH Draw the structure of D-sorbital. s. (4 pts) Classify the following amino acid as polar, non- polar, acidic, or basic: 6 (4 pts) The amino acid threonine (thr) has two chiral carbons. Draw a Fischer projection of the 2S,3S configuration of threonine. キ 7.(11 pts) Draw the tripeptide lys-asp-ser at physiological pH 8. (8 pts) The pK, values for aspartic acid are 2.10, 9.82...