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Of the following substances, the establishment of tolerance is more difficult with: A) proteins B) haptenic...

Of the following substances, the establishment of tolerance is more difficult with:

A) proteins

B) haptenic groups

C) polysaccharides

D) particulate antigens

E) synthetic polypeptides

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Answer #1

Tolerance means 'the ability to withstand stress'.

Among the given, establishment of tolerance is most difficult in particulate antigens. Antigens are small molecules in our body which are harmful. Antibodies protect our body against antigens. Antigens are generally not tolerant towards antibodies. As and when they encounter antibodies, an agglutination reacts occurs; resulting in destruction of the antigen.

Experiments have shown that establishment of tolerance generally fails in small antigens. So, among the given options 'D' is the correct answer.

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