Question

In your BLAST search for homologs of the Salmonella RtcR regulatory protein, you found multiple homologs in a Klebsiella species that were likely to be bEBPs controlling various operons in the sigma54 regulon of Klebsiella. These homologues in Klebsiella are likely paralogs. What is the likely mechanism for evolution of these transcriptional regulators?

A) Horizontal gene transfer of multiple genes by transduction

B) Horizontal gene transfer of multiple genes by transformation

C) Duplication and divergent evolution through mutation

D) Horizontal gene transfer of multiple genes by conjugation

Answer 1

Answer: Option C

Explanation:

• Here in this scenario they have given that these homologous in Klebsiella are likely paralogs.
• Paralog homologous sequences are obtained by gene duplication and speciation event.
• And speciation occurs due to divergent evolution.