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Why are most biofilms resistant to many forms of sterilization? They are too big for antibiotics to penetrate The extracelluar matrix helps protect against antibiotic treatment. Because most treatments dont know how to handle the Archaea species and they prevail Most likely from gene swapping from HGT They are just as susceptible to sterilization as any other prokaryote

The answer is not B (extracellular) or C (Archaea)

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Answer #1

The answer must be option A. They are too big for antibiotics to penetrate.

Biofilms are a consortium of bacteria that stick to each other or the surface on which they grow. This nature of growing together makes them a mass kind of a structure and it is hard for the antibiotics to penetrate the biofilm and affect each cell in the consortium. Hence, their level of organisation as a biofilm makes them resistant to many forms of sterilisation.

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