What alkene is formed when 1-bromo-4-methylcyclohexane reacts with sodium ethoxide as the base, in ethanol solvent. (elimination) Is the alkene chiral or achiral? Are there any stereoisomers of this alkene?
What alkene is formed when 1-bromo-4-methylcyclohexane reacts with sodium ethoxide as the base, in ethanol solvent....
Following are two diastereomers of 3-bromo-3, 4-dimethylhexane. On treatment with sodium ethoxide in ethanol, each gives 3, 4-dimethyl-3-hexene as the major product. One diastereomer gives the E alkene, and the other gives the Z alkene. Which diastereomer gives the E alkene? Following are two diastereomers of 3-bromo-2, 3, 4-trimethylhexane. On treatment with sodium ethoxide in ethanol, each gives 23, 4-trimethyl-3-hexene as the major product. One diastereomer gives the E alkene, and the other gives the Z alkene. Which diastereomer gives...
4. When 1-iodo-1-methylcyclohexane is treated with sodium ethoxide, the more highly substituted alkene product predominates. Alternatively, when potassium tert-butoxide is used as a base, the less substitute alkene predominates. Give the structures of the two bases, and the two products and explain the difference in regioselectivity. 5. Draw the diastereomer of the compound shown below. Explain which chair conformation one will react faster in the presence of a strong base to give a substituted cyclohexene. (Draw the chair structure of...
(a) When cis-1-bromo-2-methylcyclohexane undergoes an E2 reaction, two products (cycloalkenes) are formed. What are these two cycloalkenes, and which would you expect to be the major product? Write conformational structures showing how each is formed. (b) When trans-1-bromo-2-methylcyclohexane reacts in an E2 reaction, only one cyclo- alkene is formed. What is this product? Write conformational structures showing why it is the only product.
4. The reaction between cis-1-bromo-2-methylcyclohexane and ethoxide (a very strong base) results in an E2 reaction. (refer to Mechanism 9.8 in your textbook) a. Show the transition state for this reaction. CHE + CH, CH, CH, OH b. Show the formation of the product(s) from the transition state. c. Use the rule from part 3d, to determine the major and minor alkene products.
What product(s) are expected in the ethoxide-promoted ?-elimination reaction of 1-chloro-1-methylcyclohexane? Omit ions, salts, and ethanol from your response. What product(s) are expected in the ethoxide-promoted beta-elimination reaction of 1-chloro-1-methylcyclohexane? Omit ions, salts, and ethanol from your response.
a. What product(s) are expected in the ethoxide-promoted ß-elimination reaction of 1-chloro-1-methylcyclohexane? Omit ions, salts, and ethanol from your response. b. What product(s) are expected in the ethoxide-promoted ß-elimination reaction of 2-bromo-2,3-dimethylbutane? Omit ions, salts, and ethanol from your response.
cis-1-bromo-4-tert-butylcyclohexane and trans-1-bromo-4-tert-butylcyclohexane both react with sodium ethoxide in ethanol to give 4-tert-butylcyclohexene. However, one of the isomers reacts much more rapidly than the other isomer. Predict which isomer is reacting faster by showing a mechanism for each isomer. Your answer should account for the slower reacting substrate.
In a Williamson ether synthesis with sodium ethoxide and 1-bromobutane, with ethanol as the solvent, which substances would be distilled and which substance would distill first?
8) When 1-bromo-2 methylcyclohexane is treated with methanol and heat, four different products are formed- two by substitution and two by elimination. Provide plausible mechanisms for each product (individually). (5 pts each) OCH3 CH3 CH2 CH3 CH3 OCH3
What product(s) are expected in the ethoxide-promoted ?-elimination reaction of 2-bromo-2,3-dimethylbutane? Omit ions, salts, and ethanol from your response.