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In humans, the mother's antibodies do not cross....

5. In humans, the mothers antibodies do not cross from the babys gut into the bloodstream. Yet human breast milk contains antibodies and does protect against intestinal infections. Discuss how these antibodies might work.
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The new bron infants receive passive immunity through mother. The maternal antibodies cross the placenta and enter the fetus to provide protection. These include IgG antibodies. These are circulated in blood. The infants after birth also receive antibodies through breast feeding of mother's milk. The breast milk produced immediately after birth is called colostrum. This milk is rich in secretory antibodies like IgA.

These antibodies penetrate mucosal surfaces of mouth, air passage, throat and intestinal cells and colonize along with microorganisms. The antibodies are not directly released into circulation. Since, the stomach acid not sufficiently produced in infants they are frequently prone to intestinal infections. Thus, the IgA antibodies penetrated the gut mucosa through breast milk protect against the intestinal pathogens.

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