10. (22pts) Complete the following synthetic road map problem by providing reagent(s) for boxes A, B,...
2. (6 pts each) Complete the following reactions by providing the correct reagent(s) or product(s). Be sure to include stereochemistry if appropriate. NH2 H',cat. H*, cat CH.CH OH H, quench t.com CH_MgBr -
Slide appropriate reactants into the boxes to conduct the following synthetic transformation. You don't ne Map to necessarily fill all the boxes, but if you don't use them all, fill from the top down. Unused boxes can be rent empty. Note: It is probably best to work these on paper, the same way you would on a test. Then once you've got your answer, look for the chemicals in the bins. When both a base and an electrophile both need...
solve the road mab with explanation 16. ROAD MAP: Compounds A, B, and Care constitutional isomers. Treatment of A or B with potassium tert-butoxide gives the same alkene D. If the base is changed to a less sterically hindered base such as sodium ethoxide, A and C give the same alkene E as the major product. Treatment of C (spectroscopic data given on next page) with potassium tert-butoxide gives yet another alkene F as a minor product. Compound B reacts...
(14 pts.) 2. A spectroscopic road map. Provide the missing reactants, intermediates, and reagents for the following synthetic scheme, based on the initial spectroscopic data. C: CeH20 IR: 1720 cm-1, strong HNMR 9.72 ppm, 1H, SE 2.40 ppm, 2H, t IR: 3300 cm1, sharp HNMR: 2.83 ppm, 1H, s 1.99 ppm, 2H, d 1.80 ppm, 1H, m 0.91 ppm, 6H, d MgBr 1) H2CrO4 2) dil. H,o 1.62 ppm, 1H, m 1.50 ppm, 2H, m 0.91 ppm, 6H, d PPh3...
4. Complete the following reactions, providing the proper stereochemistry where required. If more than one product is possible, indicate the major product. a) Bry CH Но b) 1) ВН THF CH3 2) Н,О, NaOH Hа сн, Pd сн, d) Нer ROOR e) RCO H 1) Hg(OAch, H2O 2) NaBH З/19
4. Complete the following reactions, providing the proper stereochemistry where required. If more than one product is possible, indicate the major product. a) Bry CH Но b) 1) ВН THF CH3 2) Н,О, NaOH Hа сн, Pd сн, d) Нer ROOR e) RCO H 1) Hg(OAch, H2O 2) NaBH З/19
Complete the following reaction by drawing the structure of the major product(s) expected. You do not have to consider stereochemistry. You do not have to explicitly draw H atoms. If there is more than one major product possible, draw all of them. Separate multiple products using the + sign from the drop-down menu.
Complete the following synthesis by selecting from the list of 10 reagents below. Each reagent (or set of reagents) is labeled as a letter. In the answer box, simply place the order of reagents used as uppercase letters. For example, if your synthesis involves using reagent A followed by B, followed by C, and then D, your answer would be: ABCD. NaOH NaOET 1. NaBH4 ext H2O EtOH 2. H20 A B с D E Br H30+ Ph3P=CH2 PCC heat...
Complete the following reaction by drawing the structure of the major product(s) expected. CHз H2804 CH—снссНз Н20 ? CH3 You do not have to consider stereochemistry You do not have to explicitly draw H atoms. If there is more than one major product possible, draw all of them. Separate multiple products using the sign from the drop-down menu. . ChemDoodle
Draw the most stable form of the major mixed Claisen product formed in the following reaction. 1. NaOC,H, 2. 4,0* C,H,OH Map 10 Draw the mechanism-arrows for the reaction shown. سیلا بلل NaOCH, CH,OH le line :0=CH3 A ö: :0 f Slide appropriate reactants into the boxes to conduct the following synthetic transformation. You don't ne Mapa to necessarily fill all the boxes, but if you don't use them all, fill from the top down. Unused boxes can be rent...