Question

Microtubles can be easily isolated and studied in vitro. Similarly, it is possible to examine how the molecular motors kinesin and dynein work by purifying them, tagging them appropriately, and then appylying them to isolated microtubles. In a series of experiments, you find that the addition of AMP-PNP causes the kinesin to bind to microtuble , but no movement occurs. Adding ATP, however cause kinesin to move in the expected direction. What is the most likely reason for this result, and what information does it reveal about the importance of ATP and kinesin?

Answer 1

KINESIN IS A MOTOR PROTEIN, WHICH CAN CONVERT CHEMICAL ENERGY INTO MECHANICAL ENERGY. HERE ATP PROVIDES CHEMICAL ENERGY AND THIS CHEMICAL ENERGY CONVERTED INTO MECHANICAL ENERGY BY KINESIN AND SHOW MOMENT IN SPECIFIC DIRECTION