The sequence of a Michael addition followed by an intramolecular aldol condensation is known 5. as...
Base-catalyzed crossed aldol condensation followed by the
oxa-michael addition reaction mechanism for the reaction above!
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20 10 F4 FOF2 DOO FS F9 0 A 6 7 8L 0 diiso propylamine (DIPA) EtoH + HP
The following compound undergoes an intramolecular Robinson annulation reaction consisting of a conjugate addition followed by an aldol condensation. Draw the final product. No mechanism needed. Question 3 ( 5 points ) СН3 HO molargla H3C Create OscerSketch Answer 3 Question 4 Predict the product of the following reaction sequence. Draw the single main product structure only. ( 5 points ) H3C LDA (acid workup) Create OscerSketch Answer 4
The Robinson annulation involves two sequential reactions, a
Michael addition and an aldol condensation, resulting in the
formation of a cyclohexenone derivative. Draw the structure of the
two neutral reactants required to form the product shown
below.
The Robinson annulation involves two sequential reactions, a Michael addition and an aldol condensation, resulting in the formation of a cyclohexenone derivative. Draw the structure of the two neutral reactants required to form the product shown below.
which of the following molecules cannot undergo an
intramolecular aldol condensation when treated with NaOH
Which of the following molecules cannot undergo an intramolecular aldol condensation when treated with NaOH
Draw the organic product(s) of this intramolecular aldol
condensation reaction. Consider only the formation of 5- and
6-membered rings.
base Draw the organic product(s) of this intramolecular aldol condensation reaction. Consider only the formation of 5-and 6 membered rings. You do not have to consider stereochemistry. You do not have to explicitly draw H atoms. Do not include lone pairs in your answer. They will not be considered in the grading . Draw one structure per sketcher. Add additional sketchers...
Draw the mechanism and product for the Intramolecular Aldol condensation. Assume added at the end of the reaction
Draw the major product of the following reaction that begins with a retro-aldol, followed by an intramolecular aldol condensation. (5 points) OH OH C7H100 H20 heat
4) Jasmone, which contributes to the odor of jasmine, can be prepared by intramolecular aldol condensation of a diketone. What is the structure of the diketone?
Draw the product of the following reaction sequence
Draw the product of the following reaction sequence KOH CH, OH Incorrect The structure you have drawn is the product of a Michael reaction. Under the basic conditions, this product undergoes a further intramolecular aldol condensation reaction. Identify the enolate that forms under the basic reaction conditions and draw the product of the aldol dehydration.
Draw the product of the following reaction sequence KOH CH, OH Incorrect The structure you have drawn...