Question

QUESTION 1 Which of the following will not undergo an aldol condensation reaction? butanal C 2-methylbutanal C 2,2-dimethylbutanal 3,3-dimethyl-2-butanone QUESTION 2 Which of the following constitutes a difference between an aldol and a Claisen condensation? basic conditions Ctetrahedral intermediate Cenolate ion formation protonation of the intermediate QUESTION 3 The product of an aldol condensation reaction is generally favored if Can unsymmetrical ketone and aldehyde are used Can unsymmetrical ester and ketone are used Cone of the carbonyl partners contains no alpha hydrogens substituents near the carbonyl are large.

Answer 1

Q.1+ Conditim for aldol Reaction. fer aldol reaction thies must be a rogen next to the al diny de I ar ketone present. - Butanal - - honu Butanal o 22- hydrogen present e al dol Reaction. IL 2-methy Butanal 1 me la-Hydrogen present rence it also will give aldol Reaction 2,2- dimethyl Butanol rence do not undergoes. aldol Reaction. me me don't have x-hyclrogen 3,3-dimethyl-2-butanone n met me under 3&-hydrogen Aldol conder nahas. Hence it will goes Reaction henu any compound having a - hydrogen with wespeel respect to a - Aldehych a Ketone give aldol reachen as 2 methyl Butanal don't have - hydrogen. Hence that will not undergoes. aldol reaction.

- Dixferenu between Aldol and cloisen com annation. aldigde or ketone having a - hydrogen an. V treatment with aid or Bass undergoes, Aldol Reaction - Extes having a hydrogen, on treatment with acid or Bare indergoes claisen an den eation. @ Aldol ои Naou & u naon Barn mich Enolate fermation - Tefahyaral Intermediche] Protonation on rence en aldol all given fores condition. are used - Basic © Te pranycoal Intermediate DA ③ Enoscete is formation proto notes of intermediate.

Claisen Reaction & Lo + , o Navet -06 2 Okt exter mechanism t n i formohen of and late g Na besi base cu 067 -0ef Foot + 06 I out [Tetrangdral Interme click Hence in claisen anly cmdinm fulfils 0 Basic condinin o onolote in formahan ③ Tepany docel Intermediate and runce dexxerence between aldol and claisen is pooronation of Intermediate which in ocurre in aldol not is. cleisen.

Q-3 ☺ an cnsyomedical Ketone) aldehyde ач сү4, we take unsymmetriced ketone alderde then Imolate formation can tokes place from bithen tide and hence two one three type of product will obtain 6 on insymmetrical Eates and a kerne are used In this case Reaxitim is known as mixed - caldal and Rate of Reachon is also low dau to less Electrophilic centre of Exter 6 one of coobonge portres contain's no 2- ny doo qens. this conditim favoura generally good oldol Reachon with high Rate. @ Subatituenty near the carbonyl are A large dal to steric nindrane large subtituents the Intermediate Reaction will be undtable and hence Rate of Reaction will be ere. according to above statment options - t will give good celdol Reaction. y hope you like the explaination. af all the Question. 7 you can Rate me by Thimble up.