Nucleophilic sites - Where there is a excess of electron or negative charge it acts as nucleophilic sites.
Electrophilic sites - Where there is a deficient of electron or positive charge it acts as electrophilic site.
1. Label all electrophilic (El) and nucleophilic (Nu) sites on the following molecules. BYYY OH
For each of the sites specified in the following molecules, indicate whether the site is nucleophilic, electrophilic, or neither by dragging the appropriate label to the box pointing to the site. For each of the sites specified in the following molecules, indicate whether the site is nucleophilic, electrophilic, or neither by dragging the appropriate label to the box pointing to the site.
8. Identify the nucleophilic and electrophilic sites (one of each) in the two reactants in the following reaction. HOME Гоме
18. Classify the following molecules in terms of how fast they will undergo nucleophilic aromatic substitution, label them as "fast S.Ar. Label the ones that would be fast under electrophilic aromatic substitution as "fast Ear. Those that would not react label as neither. NO,
In carbonyl condensation reactions, the carbonyl is neither electrophilic nor nucleophilic both electrophilic and nucleophilic electrophilic nucleophilic Question 20 Give the major product of the following sequence of reactions: 1) HNOZ/H2SO4 acetophenone 2) H/Pd p-aminoethylbenzene m-aminoethylbenzene m-aminoacetophenone m-nitroacetophenone MacBook Pro DD DOO 80 DII FS F7 F4 FS & 7 * oC 6 9
In carbonyl condensation reactions, the carbonyl is neither electrophilic nor nucleophilic both electrophilic and nucleophilic electrophilic nucleophilic Question 20 Give the major product of the following sequence of reactions: 1) HNO/H2SO4 acetophenone 2) H/Pd Op-aminoethylbenzene m-aminoethylbenzene m-aminoacetophenone m-nitroacetophenone MacBook Pro COO 80 DIN FB DOO F7 F9 F6 FS % & * < CC 7 8
O H2N-OH 2. нса a Electrophilic addition b-E2 Elimination d- Sy2 Nucleophilic substitution-Nucleophilic subs at carbonyl(acyl Xfer) e-Electrophilic aromatic substitution h -Conjugate (nucleophilic) addn SNI Nucleophilic substitution r-Carbonyl nucleophilic addn Identify the mechanism by which each of the reactions above proceeds from among the mechanisms listed. Use the letters a -i for your answers. 2. Submit Answor Retry Entire Group 9 more group attempts remaining
1) Label all the chiral molecules with a circle. Label all meso compounds with a square. (3 ps) OH OH OH CI. BO CI, Br
Classify the circled atom as nucleophilic, electrophilic, or neither. Select one: O a. Nucleophilic O b. Electrophilic c. Neither Draw the mechanism for the following SN1 reaction. Indicate which of the following statements is true. Select all correct answers to receive full credit. Cl +NaF Select one or more: a. The mechanism involves only a loss of leaving group and a nucleophilic attack and no other steps. b. A carbocation rearrangement occurs. c. The first step is a proton transfer....
N(CH3)3 OH 1. heat 95% 5% (E & Z) он 2. H2N a - Proton transfer dSN2 Nucleophilic substitution b- Lewis acid/base e-Electrophilic aromatic substitution c=E2 elimination f= g Nucleophilic subs at carbonyl(acyl Xfer) h-Conjugate (nucleophilic) addn r-carbonyl nucleophilic addn Identify the mechanism by which each of the reactions above proceeds from among the mechanisms listed. Use the letters a i for your answers. 1. 2. N(CH3)3 OH 1. heat 95% 5% (E & Z) он 2. H2N a -...
4. Identify all electrophilic positions in compound A and all nucleophilic positions in compound B given below: Br N-H CI CI Compound A Compound B