3. (15 pts.) Provide retro- and forward syntheses of the following compound from the indicated starting...
5. (Total 15 pts.) Provide the synthesis of the following compound from the mentioned starting materials. You are strongly advised to provide the retro-synthetic analysis before drawing the synthetic sequence. Show all reagents required for each transformation Retrosynthesis: Forward Synthesis: 60f 16 649 words English (United States Focus
4. Synthesize the following compound from starting materials containing the indi cated number of carbons. Show your syntheses in the forward direction and include any necessary reactants, reagents or catalysts. Do NOT provide mechanisms. (25 pts)
4. Synthesize the following compound from starting materials containing the indi cated number of carbons. Show your syntheses in the forward direction and include any necessary reactants, reagents or catalysts. Do NOT provide mechanisms. (25 pts)
please show all steps with necessary mechanism arrows
1. Provide the starting specific nucleophile and electrophile that would result in each of the following molecules using an SN2 reaction. Do consider the ABC and provide the specific reagent necessary. (2 points) Me HH MeMe Me I wyn Me Me 2. Provide a detailed retrosynthesis and synthesis of the following compound from the indicated starting material. All atoms of the target must come from the indicated starting materials. You may use...
12) Starting with hex-3-en-2-one, propose syntheses for the following compound the following (8 pts total): propose syntheses for the following compounds. For each synthesis, indicate op that needs to be done to add functional groun (ex: reduction: dehydration: Grignard, etc.) - include reagents required for the transformation (ex: NaBH, for carbonyl reduction, etc.) OH MY OH *Hint: refer to g. 11
3. Show efficient syntheses of each of the following from the indicated compound and any need organic or inorganic reagents. (50 pts) (a) 1-popene, from 1-bromopropane (b) 1-chloro-2-butanol, 1-bromobutane (c) 2-pentyne, from propyne (d) trans-1,2-dibromocyclohexane, from cyclohexanol (e) 2,3-hexanediol, from 2-hexene
3. Show efficient syntheses of each of the following from the indicated compound and any need organic or inorganic reagents. (50 pts) (a) 1-popene, from 1-bromopropane (b) 1-chloro-2-butanol, 1-bromobutane (c) 2-pentyne, from propyne (d) trans-1,2-dibromocyclohexane, from cyclohexanol (e) 2,3-hexanediol,...
3 e f g
3. Suggest efficient syntheses for the following compounds, starting from the compound indicated and any other needed reagents. (98 pts) e) benzonitrile (C HsCEN) starting from benzene. (f) octanoic acid, from 1-hexanol. (g) phenol, from aniline (CsHsNH:).
Show how you would use Grignard syntheses to prepare the
following alcohols from the indicated starting materials and any
other necessary reagents. Draw the Grignard reagent and any other
organic reagents needed.
11 RUVIUWI Constans i Pendulu Part F Show how you would use Grignard syntheses to prepare the following alcohols from the indicated starting materials and any other necessary reagents. Draw the Grignard reagent and any other organic reagents needed. ОН -C-CH CH, from C-OCH.CH Draw the molecules on...
Show how you would use Grignard syntheses to prepare the following alcohols from the indicated starting materials and other necessary reagents. a) octan-3-ol from hexanal, CH3(CH2)4CHO
Propose syntheses of the given compounds from the indicated
starting materials.
он NH2 CH30
1. (6 pts) Provide two different syntheses for 1,1-diphenyl-1-butanol starting from a carbonyl compound and using a Grignard reagent. Synthetic Route 1: carbonyl Grignard reagent a) THE b) H30* work up 1,1-diphenyl-1-butanol Synthetic Route 2: carbonyl Grignard reagent a) THF b) H30* work up ОН 1.1-diphenyl-1-butanol 2. (3 pts) The use of Grignard reagents requires scrupulously dry aprotic solvents such as diethyl ether or tetrahydrofuran. Please explain why the solvents need to be scrupulously dry. To support your reason, show...