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Question 13 of 24 Analyze the biological compounds shown and identify the number of aromatic rings...
Activity of aromatic ring with CYP450: 2. (2.3 points) Each of the drugs below contain 3...
Activity of aromatic ring with CYP450:
2. (2.3 points) Each of the drugs below contain 3 aromatic rings. (a) For ONE of the compounds, rank each ring as 1, 2, and 3, in order of their likelihood of undergoing a CYP-450 mediated oxidation, and briefly explain your answers. (b) Then draw an arrow to show the most likely site of oxidation in the most reactive ring. gorac -NO2 Br enclomiphene (antiestrogen) HO celecoxib-like (anti-inflammatory) CO2Na ОН CF3 IZ O=D=0 N...
PLEASE ANSWER ALL QUESTIONS 34) Which sequence correctly ranks the following aromatic rings in order of...
PLEASE ANSWER ALL QUESTIONS
34) Which sequence correctly ranks the following aromatic rings in order of increasing rate of reactivity in an electrophilic aromatic substitution reaction? LOCH A) 1<2<3 B) 2 <3 <1 C) 3 <1<2 D) 2 <1<3 35) Derivatives of the compound shown below are currently being examined for their effectiveness in treating drug addiction and metabolic syndrome (J. Med. Chem. 2006, 872). Which sequence ranks the following aromatic rings of this compound in order of increasing reactivity...
For each of the species below, identify any cyclic conjugated system, then A. Determine the number...
For each of the species below, identify any cyclic conjugated system, then A. Determine the number of electrons in a system of cyclic conjugation (zero if no cyclic conjugation). B. Specify whether the species is "a-aromatic, "aa' anti-aromatic, or "na"-non-aromatic (neither aromatic nor anti-aromatic). (Presume rings to be planar unless structure obviously prevents planarity. If there is more than one conjugated ring, count electrons in the largest A.Electrons in a cyclic conjugated system B.The compound is (a, aa, or na)...
C) E1 D) E2 E) E1cb 24. Rank is first, slowest is last) the following compounds...
C) E1 D) E2 E) E1cb 24. Rank is first, slowest is last) the following compounds in order of increasing reacdtivity in an a veaion Br Br IV 2. In the molecular orbital representation of benzene, how many T molecular orbitals are present? A) 1 B) 2 C) 4 D) 6 E) 8 26. What is the major difference between an antiaromatic and aromatic compound? A) The structure must be cyclic for aromatic but not antiaromatic compounds. B) Antiaromatic compounds...
QUESTION 19 Which of the following compounds are aromatic? Choose all possible compounds. Assume all completely...
QUESTION 19 Which of the following compounds are aromatic? Choose all possible compounds. Assume all completely conjugated rings are planar. Coop oooo a, cd a, b, d, e b,cd a, b,c,d QUESTION 20 Save All Answers Close me Click Save and submit to save and submit. Click Save All Answers to save all answers QUESTION 20 Rank the following compounds in order of increasing reactivity in nucleophilic acyl substitution (from least to most OMe NH2 | CAB Β< <Α С...
For each of the species below, identify any cyclic conjugated system, then: A. Determine the number...
For each of the species below, identify any cyclic conjugated system, then: A. Determine the number of electrons in a system of cyclic conjugation (zero if no cyclic conjugation). B. Specify whether the species is "a"-aromatic, "aa"-anti-aromatic, or "na"-non-aromatic (neither aromatic nor anti- aromatic). (Presume rings to be planar unless structure obviously prevents planarity. If there is more than one conjugated ring, count electrons in the largest.) A.Electrons in a cyclic conjugated system. B.The compound is (a, aa, or na)...
Thanks! For each of the species below, identify any cyclic conjugated system, then: A. Determine the...
Thanks!
For each of the species below, identify any cyclic conjugated system, then: A. Determine the number of electrons in a system of cyclic conjugation (zero if no cyclic conjugation) B. Specify whether the species is "a"-aromatic, "aa"-anti-aromatic, or "na"-non-aromatic (neither aromatic nor anti-aromatic). (Presume rings to be planar unless structure obviously prevents planarity. If there is more than one conjugated ring, count electrons in the largest.) 1. A.Electrons in a cyclic conjugated system B.The compound is (a, aa, or...
There are several aromatic compounds with the formula CgH9Cl. Name those that have a trisubstituted ring...
There are several aromatic compounds with the formula CgH9Cl. Name those that have a trisubstituted ring where the methyl groups are oriented meta. If you choose to use ortho, meta, or para in your name, abbreviate these prefixes with o, m, or p. If there are not 3 isomers that fit the description, leave the appropriate number of spaces blank. Isomer #1: Isomer #2: Isomer #3:
For each of the species below, identify any cyclic conjugated system, then A. Determine the number...
For each of the species below, identify any cyclic conjugated system, then A. Determine the number of electrons in a system of cyclic conjugation (zero if no cyclic conjugation). B. Specify whether the species is "a"-aromatic, "aa"-anti-aromatic, or "na"-non-aromatic (neither aromatic nor anti-aromatic) (Presume rings to be planar unless structure obviously prevents planarity. If there is more than one conjugated ring, count electrons in the largest.) 1. H A.Electrons in a cyclic conjugated system B.The compound is (a, aa, or...
For each of the species below, identify any cyclic conjugated system, then: 1. Determine the number...
For each of the species below, identify any cyclic conjugated
system, then:
1. Determine the number of electrons in a system
of cyclic conjugation (zero if no cyclic conjugation).
2. Specify whether the species is
"a"-aromatic, "aa"-anti-aromatic,
or "na"-non-aromatic (neither aromatic nor
anti-aromatic).
(Presume rings to be planar unless structure obviously prevents
planarity. If there is more than one conjugated ring, count
electrons in the largest.)
please help with these study guide questions; I always thumbs
up, thank you for...
Activity of aromatic ring with CYP450:
2. (2.3 points) Each of the drugs below contain 3 aromatic rings. (a) For ONE of the compounds, rank each ring as 1, 2, and 3, in order of their likelihood of undergoing a CYP-450 mediated oxidation, and briefly explain your answers. (b) Then draw an arrow to show the most likely site of oxidation in the most reactive ring. gorac -NO2 Br enclomiphene (antiestrogen) HO celecoxib-like (anti-inflammatory) CO2Na ОН CF3 IZ O=D=0 N...
PLEASE ANSWER ALL QUESTIONS
34) Which sequence correctly ranks the following aromatic rings in order of increasing rate of reactivity in an electrophilic aromatic substitution reaction? LOCH A) 1<2<3 B) 2 <3 <1 C) 3 <1<2 D) 2 <1<3 35) Derivatives of the compound shown below are currently being examined for their effectiveness in treating drug addiction and metabolic syndrome (J. Med. Chem. 2006, 872). Which sequence ranks the following aromatic rings of this compound in order of increasing reactivity...
For each of the species below, identify any cyclic conjugated system, then A. Determine the number of electrons in a system of cyclic conjugation (zero if no cyclic conjugation). B. Specify whether the species is "a-aromatic, "aa' anti-aromatic, or "na"-non-aromatic (neither aromatic nor anti-aromatic). (Presume rings to be planar unless structure obviously prevents planarity. If there is more than one conjugated ring, count electrons in the largest A.Electrons in a cyclic conjugated system B.The compound is (a, aa, or na)...
C) E1 D) E2 E) E1cb 24. Rank is first, slowest is last) the following compounds in order of increasing reacdtivity in an a veaion Br Br IV 2. In the molecular orbital representation of benzene, how many T molecular orbitals are present? A) 1 B) 2 C) 4 D) 6 E) 8 26. What is the major difference between an antiaromatic and aromatic compound? A) The structure must be cyclic for aromatic but not antiaromatic compounds. B) Antiaromatic compounds...
QUESTION 19 Which of the following compounds are aromatic? Choose all possible compounds. Assume all completely conjugated rings are planar. Coop oooo a, cd a, b, d, e b,cd a, b,c,d QUESTION 20 Save All Answers Close me Click Save and submit to save and submit. Click Save All Answers to save all answers QUESTION 20 Rank the following compounds in order of increasing reactivity in nucleophilic acyl substitution (from least to most OMe NH2 | CAB Β< <Α С...
For each of the species below, identify any cyclic conjugated system, then: A. Determine the number of electrons in a system of cyclic conjugation (zero if no cyclic conjugation). B. Specify whether the species is "a"-aromatic, "aa"-anti-aromatic, or "na"-non-aromatic (neither aromatic nor anti- aromatic). (Presume rings to be planar unless structure obviously prevents planarity. If there is more than one conjugated ring, count electrons in the largest.) A.Electrons in a cyclic conjugated system. B.The compound is (a, aa, or na)...
Thanks!
For each of the species below, identify any cyclic conjugated system, then: A. Determine the number of electrons in a system of cyclic conjugation (zero if no cyclic conjugation) B. Specify whether the species is "a"-aromatic, "aa"-anti-aromatic, or "na"-non-aromatic (neither aromatic nor anti-aromatic). (Presume rings to be planar unless structure obviously prevents planarity. If there is more than one conjugated ring, count electrons in the largest.) 1. A.Electrons in a cyclic conjugated system B.The compound is (a, aa, or...
There are several aromatic compounds with the formula CgH9Cl. Name those that have a trisubstituted ring where the methyl groups are oriented meta. If you choose to use ortho, meta, or para in your name, abbreviate these prefixes with o, m, or p. If there are not 3 isomers that fit the description, leave the appropriate number of spaces blank. Isomer #1: Isomer #2: Isomer #3:
For each of the species below, identify any cyclic conjugated system, then A. Determine the number of electrons in a system of cyclic conjugation (zero if no cyclic conjugation). B. Specify whether the species is "a"-aromatic, "aa"-anti-aromatic, or "na"-non-aromatic (neither aromatic nor anti-aromatic) (Presume rings to be planar unless structure obviously prevents planarity. If there is more than one conjugated ring, count electrons in the largest.) 1. H A.Electrons in a cyclic conjugated system B.The compound is (a, aa, or...
For each of the species below, identify any cyclic conjugated
system, then:
1. Determine the number of electrons in a system
of cyclic conjugation (zero if no cyclic conjugation).
2. Specify whether the species is
"a"-aromatic, "aa"-anti-aromatic,
or "na"-non-aromatic (neither aromatic nor
anti-aromatic).
(Presume rings to be planar unless structure obviously prevents
planarity. If there is more than one conjugated ring, count
electrons in the largest.)
please help with these study guide questions; I always thumbs
up, thank you for...
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