What is the charge on Br ion before it is attached to the alpha carbon? (No...
7. What two molecules could be used to make the following molecules using crossed aldol reaction. ook OH 8a. There are 4 alpha-carbons in this molecule. Which alpha carbon(s) is/are the most reactive? What is the product if NaOH and heat are used? a 8b. What is the scientist name whom the above reaction is named after? 9. Why does the base (used to proton transfer) need match the initial reactant in the Claisen Condensation? 10. Malonic ester synthesis questions...
7. What two molecules could be used to make the following molecules using crossed aldol reaction. OH 8a. There are 4 alpha-carbons in this molecule. Which alpha carbon(s) is/are the most reactive? What is the product if NaOH and heat are used? 8b. What is the scientist name whom the above reaction is named after? 9. Why does the base (used to proton transfer) need match the initial reactant in the Claisen Condensation? 10. Malonic ester synthesis questions - Show...
7. What two molecules could be used to make the following molecules using crossed aldol reaction. O ook OH 8a. There are 4 alpha-carbons in this molecule. Which alpha carbon(s) is/are the most reactive? What is the product if NaOH and heat are used? 8b. What is the scientist name whom the above reaction is named after? 9. Why does the base (used to proton transfer) need match the initial reactant in the Claisen Condensation? 10. Malonic ester synthesis questions...
**(left structure)****(right
structure)**
The two structures for the assignment are above and
the task is:
1. Perform a retrosynthetic analysis on the two target
molecules assigned to you. In each case the organic
starting material (what you have to work backwards toward) depends
upon the target. For the structure given above (structure on left),
the starting material is either malonic ester or acetoacetic ester
and any halide. For the structure given above (structure on right),
the starting material is any...
What is the IUPAC name of the given molecule? OH Br 1-bromo-2-ethyl-2-hydroxy-3-methylpentanoic acid 2-ethyl-3-methylpentan-2-ol-1-carboxyl bromide 2-ethyl-3-methyl-2-ol-pentanoyl bromide O2-ethyl-2-hydroxy-3-methylpentanoyl bromide What statement is TRUE about the mechanism for the reaction shown here? CH,(CH)2CO,CH, NaOH CH3(CH12COCH excess heat CH3(CH)2CO,CH2 Water attacks the carbonyl carbon to form a tetrahedral intermediate. The first step of the reaction involves protonation of the ester carbonyl oxygen. One of the products formed is glycerol. The hydroxide deprotonates the alpha carbon. Which bases among the following is/are used...
Page 1 Synthesis using Carbonyl O-Substitution Chemistry Preamble This experiment involves the synthesis of target molecules using a-substitution chemistry. You are assigned two target molecules, one of which is best synthesized by an alkylation approach, while the other is best synthesized by an addition or condensation approach. You must do the following: 1. Perform a retrosynthetic analysis on the two target molecules assigned to you. In each case the organic starting material (what you have to work backwards toward) depends...
Synthesis using Carbonyla-Substitution Chemistry Preamble This experiment involves the synthesis of target molecules using a-substitution chemistry. You are assigned two target molecules, one of which is best synthesized by an alkylation approach, while the other is best synthesized by an addition or condensation approach. My two target molecules are number 2 and number 12 in the last page. You must do the following: 1. Perform a retrosynthetic analysis on the two target molecules assigned to you. In each case the...
a. First, circle the leaving group and label the alpha carbon as a. b. Then, label the adjacent sp3 beta carbons as B. c. Finally, draw in the H's that can get eliminated along with the leaving group in each of these compounds. The first compound has been completed for you. HH می ) و CH3 2. Now, let's perform the elimination to make the Zaitsev (most substituted) product. Draw in the H from before and the curved arrows to...
Thank you!
9. What would be the product of the following conversion? 1. NaOEt, EIOH OEt 2. H,о- OEt ОН О OEt OEt OEt OE OEt e. d. 10. What is the product of the Dieckmann condensation of the following diester? 1.NaOCH, CH,Oн HgCOoc coOCHs 2. H,0* осн, COOCH COOCH b. d. both a) and b) e. a), b), and c) a. C. 11. Consider the synthesis below. What is compound X? COOEt COOH 1. КОВи 1. NAOH, H2O, heat...
What is the correct name for the following compound? d) 5-oxo-3-octenoic acid What is the defining functional group of a carboxylic acid? a) an-H attached to a carbonyl group b) an-H attached to a carbon-carbon triple bond c) an-OH attached to a carbonyl group d) an -OH group attached to a O-C double bond e) an-OH group attached to an aromatic ring To convert a carboxylic acid to an aldehyde a) convert the acid to an acid chloride, then use...