Explain the mechanisms of synthesis and the biological role of eicosanoids and their clinical application (prostaglandins, prostacyclines)
All mammalian cells except erythrocytes synthesize eicosanoids. Two main pathways are involved in the biosynthesis of eicosanoids, the cyclic and the linear pathways. The prostaglandins and thromboxanes are synthesized by the cyclic pathway, the leukotrienes are synthesized by the linear pathway.
Eicosanoids function in diverse physiological systems and pathological processes such as: mounting or inhibiting inflammation, allergy, fever and other immune responses; regulating the abortion of pregnancy and normal childbirth; contributing to the perception of pain; regulating cell growth; controlling blood pressure; and modulating the regional flow of blood to tissues.
Explain the mechanisms of synthesis and the biological role of eicosanoids and their clinical application (prostaglandins,...
Prostaglandins are a class of eicosanoids, fatty acid derivatives with a variety of extremely potent actions on vertebrate tissues. They are responsible for producing fever and inflammation and its associated pain. Prostaglandins are derived from the 20-carbon fatty acid arachidonic acid in a reaction catalyzed by the enzyme prostaglandin endoperoxide synthase. This enzyme, a cyclooxygenase, uses oxygen to convert arachidonic acid to PGG2, the immediate precursor of many different prostaglandins. Arachidonic Rate of formation Rate of formation of PGG2 with...
Prostaglandins are a class of eicosanoids, fatty acid derivatives with a variety of extremely potent actions on vertebrate tissues. They are responsible for producing fever and inflammation and its associated pain. Prostaglandins are derived from the 20-carbon fatty acid arachidonic acid in a reaction catalyzed by the enzyme prostaglandin endoperoxide synthase. This enzyme, a cyclooxygenase, uses oxygen to convert arachidonic acid to PGG2, the immediate precursor of many different prostaglandins. Arachidonic acid (mM) Rate of formation of PGG2 (mM/min) Rate...
Prostaglandins are a class of eicosanoids, fatty acid derivatives with a variety of extremely potent actions on vertebrate tissues. They are responsible for producing fever and inflammation and its associated pain. Prostaglandins are derived from the 20-carbon fatty acid arachidonic acid in a reaction catalyzed by the enzyme prostaglandin endoperoxide synthase. This enzyme, a cyclooxygenase, uses oxygen to convert arachidonic acid to PGG2, the immediate precursor of many different prostaglandins. Arachidonic acid (MM) 0.245 0.294 Rate of formation of PGG2...
13 unread)-nicky Resources | Marietta Jump to... Prostaglandins are a class of eicosanoids, fatty acid derivatives with a variety of extremely potent actions on vertebrate tissues. They are responsible for Prostaglandins are derived from the 20-carbon enzyme prostaglandin endoperoxide synthase. This enzyme, a cyclooxygenase, uses oxygen to conver arachidonic acid to PGG2, the immediate precursor of many different prostaglandins. fever and inflammation and its associated pain. arachidonic acid in a reaction catalyzed by t (a) The kinetic data given in...
Explain the role of biological, psychological, and sociocultural forces in the life cycle.
Discuss the elements of psychotherapy and give a clinical example of each. Explain the biological basis of anxiety and discuss in general the priorities for treatment using the practice treatment hierarchy.
Explain how the Geometric structure of a Biological molecule plays a role in its function.
Explain the role of the health professional in transforming clinical decision-making process
Explain the role of clinical terminologies and data standards in health information exchange(HIE.)
A researcher at Lund University is interested in studying the biological role of a so-called type I nuclear receptor (steroid receptor). To do this, the transcription factor was overexpressed by transfection of a plasmid, and then effects on gene expression in the cell were examined .A: In the current experiment, the researcher attempted to influence the function of the transcription factor by increasing its amount. Hormones and other extracellular signals often use other, more rapid-acting, mechanisms to regulate the ability...