Choose one of your favorite amino acid (except Arginine and Tyrosine), Using the charge information (1)...
Choose one of your favorite amino acid (except Arginine and Tyrosine), Using the charge information (1) Write your chosen amino acid structures for sequential deprotonation and place p?? values over the equilibrium arrows (2) Calculate net charge of your chosen amino acid structures above (3) Determine pH range of amino acid based on given structure and charge (4) Calculate pI of your chosen amino acid
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Choose one of your favorite amino acid (except Arginine and
Tyrosine), Using the charge information (1)...
Name_Rachel A Date TITILLEELELE PROTEINSI Questions 1. Which amino acids used in this experiment have acidic...
Name_Rachel A Date TITILLEELELE PROTEINSI Questions 1. Which amino acids used in this experiment have acidic R-groups, which have basic R-groups, and which have neutral R-groups? Write acidic", "basic" or "neutral next to each amino acid below. • Glycine: • Glutamic acid: • Arginine: • Tyrosine: 1. Circle all the charged carboxyl groups (carboxylate groups) in the amino acid structures below. | HN-CH-- HN-CH-C-ộ HN-CH-C ó Glycine (Gly) Glutamic acid or glutamate (Glu) C=NH2 NH2 Arginine (Arg) UUUUU Proteins Chemistry...
TABLE 5.1 PK values for amino acids 2.36 Amino acid Alanine Arginine Asparagine Aspartic acid Cysteine...
TABLE 5.1 PK values for amino acids 2.36 Amino acid Alanine Arginine Asparagine Aspartic acid Cysteine Glutamic acid Glutamine Glycine Histidine Isoleucine Leucine Lysine Methionine Phenylalanine Proline Serine Threonine Tryptophan Tyrosine Valine PK, PK₂ 2.34 9.69 2.17 9.04 2.02 8.80 1.88 9.60 1.96 10.28 2.19 9.67 2.17 9.13 2.34 9.60 1.82 9.17 9.60 9.60 2.18 8.95 2.28 1.83 9.13 1.99 10.60 2.219.15 2.09 9.10 2.83 9.39 2.20 9.11 2.32 9.62 2.36 9.21 5.56. Of the amino acids listed in Table...
Consider the amino acid, glycine, in its fully protonated form + H3NCH2CO2H, where the pKa1 =...
Consider the amino acid, glycine, in its fully protonated form + H3NCH2CO2H, where the pKa1 = 2.35 and pKa2 = 9.78. a) Ka2 is the equilibrium constant for the second dissociation of + H3NCH2CO2H. Write the chemical equation that illustrates this equilibrium. b) Write the structure for the major species at pH = 1.35. c) Write the structure for the major species at pH = 3.35. d) Write the structure for the major species at pH = 10.78. e) Calculate...
Model 1 for reference, draw the structure of the given amino acid as it nly exist under each of t...
Model 1 for reference, draw the structure of the given amino acid as it nly exist under each of the following conditions for 1g.using Table 1 in a. valine; in the stomach at PH 1.5 Serine; in the small intestine at pH 10 c. Glutamate; in the blood plasma at pH 7.4 Information: Isoelectric points As shown in Model 3, amino acids do not normally exist in unionized forms. When an aminc acd contains both a (+) and a ()...
Q1) Based on your understanding of amino acid and protein topic answer the following questions. 120...
Q1) Based on your understanding of amino acid and protein topic answer the following questions. 120 points A) For the following tripeptide: Ala-Gly-Phe -OH pk2 Ala CH CH pKI 2.34 234 1.83 Gly Phe 9.60 9.13 1. Draw separate structures for the three amino acids in this tripeptide at pH=7. Opoints) 2. Calculate the pl for this tripeptide. (show your work and your answer should has two decimal points) (6 points) 3. What is the overall charge of this tripeptide...
Q1) Based on your understanding of amino acid and protein topic answer the following questions. [20...
Q1) Based on your understanding of amino acid and protein topic answer the following questions. [20 points A) For the following tripeptide: Ala-Gly-Phe O Od -CH -OH CH CH Ala Gly Phe pKI 234 2.34 1.83 pK2 9.67 9.60 9.13 1. Draw separate structures for the three amino acids in this tripeptide at pH=7. 9 points) 2. Calculate the pl for this tripeptide (show your work and your answer should has two decimal points) (6 points) 3. What is the...
1. What amino acids do the following abbreviations stand for? Draw the structure of each. a)...
1. What amino acids do the following abbreviations stand for? Draw the structure of each. a) lle b) Thr c) Gin 2. Name and draw the structures of the amino acids that fit these descriptions: a) Contains an isopropyl group b) Contains a secondary alcohol group 3. Which of the following objects is chiral? a) A pair of scissors b) A comb c) A drinking glass 4. What does the term achiral mean? Give two examples involving organic structures.. 5....
Post-Lab Questions 1. Look up the structure in your textbook of the amino acid you titrated....
Post-Lab Questions 1. Look up the structure in your textbook of the amino acid you titrated. Write the structure you expect at pH (a) 2.5 and (b) 12 2. Compare your isoelectric point value (pl value) with the value of the amino acid listed in your textbook. How does it compare? Into which class does your amino acid fall? 3. Which data point can you obtain with greater accuracy from your graph-the pK values from the "legs" or the isoelectric...
1. The pKa's of the amino acid methionine are 2.28 and 9.21. The zwitterion of methionine...
1. The pKa's of the amino acid methionine are 2.28 and 9.21. The zwitterion of methionine is given below (1). S Н,с NH3 (a) Explain why structure (I) is an intermediate ion. Write balanced chemical reactions to support your reasoning (b) Draw the conjugate acid AND conjugate base form of the amino acid shown above (c) A 15-mL aliquot solution consisted 0.25M of the zwitterion of methionine and 0.30M of its conjugate acid was titrated with 0.15M NaOH, calculate the...
#1) For the following pentapeptide (Where pH =1): a) What would the net charge be for...
#1) For the following pentapeptide (Where pH =1):
a) What would the net charge be for the following pH?
pH 0 =
pH 3 =
pH 5 =
pH 7 =
pH 10 =
pH 13 =
b) Calculate the pl of the pentapeptide. (Cysteine: pK1 = 1.96,
pK2 = 10.128) ( Glutamine: pK1 = 2.17 , pK2 = 9.13) (Arginine: pK1
= 2.17. pK2 = 9.04) (Leucine: pK1 = 2.36 , pK2 = 9.60)
c) If you were to...
Name_Rachel A Date TITILLEELELE PROTEINSI Questions 1. Which amino acids used in this experiment have acidic R-groups, which have basic R-groups, and which have neutral R-groups? Write acidic", "basic" or "neutral next to each amino acid below. • Glycine: • Glutamic acid: • Arginine: • Tyrosine: 1. Circle all the charged carboxyl groups (carboxylate groups) in the amino acid structures below. | HN-CH-- HN-CH-C-ộ HN-CH-C ó Glycine (Gly) Glutamic acid or glutamate (Glu) C=NH2 NH2 Arginine (Arg) UUUUU Proteins Chemistry...
TABLE 5.1 PK values for amino acids 2.36 Amino acid Alanine Arginine Asparagine Aspartic acid Cysteine Glutamic acid Glutamine Glycine Histidine Isoleucine Leucine Lysine Methionine Phenylalanine Proline Serine Threonine Tryptophan Tyrosine Valine PK, PK₂ 2.34 9.69 2.17 9.04 2.02 8.80 1.88 9.60 1.96 10.28 2.19 9.67 2.17 9.13 2.34 9.60 1.82 9.17 9.60 9.60 2.18 8.95 2.28 1.83 9.13 1.99 10.60 2.219.15 2.09 9.10 2.83 9.39 2.20 9.11 2.32 9.62 2.36 9.21 5.56. Of the amino acids listed in Table...
Model 1 for reference, draw the structure of the given amino acid as it nly exist under each of the following conditions for 1g.using Table 1 in a. valine; in the stomach at PH 1.5 Serine; in the small intestine at pH 10 c. Glutamate; in the blood plasma at pH 7.4 Information: Isoelectric points As shown in Model 3, amino acids do not normally exist in unionized forms. When an aminc acd contains both a (+) and a ()...
Q1) Based on your understanding of amino acid and protein topic answer the following questions. 120 points A) For the following tripeptide: Ala-Gly-Phe -OH pk2 Ala CH CH pKI 2.34 234 1.83 Gly Phe 9.60 9.13 1. Draw separate structures for the three amino acids in this tripeptide at pH=7. Opoints) 2. Calculate the pl for this tripeptide. (show your work and your answer should has two decimal points) (6 points) 3. What is the overall charge of this tripeptide...
Q1) Based on your understanding of amino acid and protein topic answer the following questions. [20 points A) For the following tripeptide: Ala-Gly-Phe O Od -CH -OH CH CH Ala Gly Phe pKI 234 2.34 1.83 pK2 9.67 9.60 9.13 1. Draw separate structures for the three amino acids in this tripeptide at pH=7. 9 points) 2. Calculate the pl for this tripeptide (show your work and your answer should has two decimal points) (6 points) 3. What is the...
1. What amino acids do the following abbreviations stand for? Draw the structure of each. a) lle b) Thr c) Gin 2. Name and draw the structures of the amino acids that fit these descriptions: a) Contains an isopropyl group b) Contains a secondary alcohol group 3. Which of the following objects is chiral? a) A pair of scissors b) A comb c) A drinking glass 4. What does the term achiral mean? Give two examples involving organic structures.. 5....
Post-Lab Questions 1. Look up the structure in your textbook of the amino acid you titrated. Write the structure you expect at pH (a) 2.5 and (b) 12 2. Compare your isoelectric point value (pl value) with the value of the amino acid listed in your textbook. How does it compare? Into which class does your amino acid fall? 3. Which data point can you obtain with greater accuracy from your graph-the pK values from the "legs" or the isoelectric...
1. The pKa's of the amino acid methionine are 2.28 and 9.21. The zwitterion of methionine is given below (1). S Н,с NH3 (a) Explain why structure (I) is an intermediate ion. Write balanced chemical reactions to support your reasoning (b) Draw the conjugate acid AND conjugate base form of the amino acid shown above (c) A 15-mL aliquot solution consisted 0.25M of the zwitterion of methionine and 0.30M of its conjugate acid was titrated with 0.15M NaOH, calculate the...
#1) For the following pentapeptide (Where pH =1):
a) What would the net charge be for the following pH?
pH 0 =
pH 3 =
pH 5 =
pH 7 =
pH 10 =
pH 13 =
b) Calculate the pl of the pentapeptide. (Cysteine: pK1 = 1.96,
pK2 = 10.128) ( Glutamine: pK1 = 2.17 , pK2 = 9.13) (Arginine: pK1
= 2.17. pK2 = 9.04) (Leucine: pK1 = 2.36 , pK2 = 9.60)
c) If you were to...
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