Question

Extra Credit: (5 pts) Rank the following compounds in order of increasing acidity. (1=least acidic, 5 = nost acidic) ان کا اور بن گیا می

Can you please list the compound in increasing acidity and the pka of each compound to explain its acidity order that it's in.

Answer 1

This problem involves important concepts of General Organic Chemistry. I give you a detailed solution as follows, Hope it will help you.

Extra Credit: (5 pts) Rank the following compounds in order of increasing acidity: (1=least acidic, 5 = most acidic) оо pkag Lpka u <pka3 < Prag Pray Explanation - The compound is most acidic because its conjugate kase is stabilised by two carbonys (-c=0) group. then the acidity of compound 4 is less that compound due to presence of ester

by two carbonys (-c=0) group then the acidity of compound 6 is less that compound ③ due to presence of ester (-0-4-) group in compound , so the conjugate base formed in compound ③, is not fully Stabilised by a group. Here conjugate base

=CH2 Here conjugate base is fully stabilised by - e=0. through Resonance structures given above Now compound 2 is less acidie than compound 3 because the stabilisation of conjugate base of compound 2 is less than compound due to high involvement of (-NH-e-) group in resonance. The high involvement occurs because the electronegativity of N is less than Orygen. So conjugate base 2

-U . TV Resonance structures above. Now compound 2 is less acidie than compound 3 because the stabilisation of conjugate base of compound 2 is less than compound ( due to high involvement of (-NH-e - group in resonance. The high involvement occurs because the electronegativity of N is less than Orygen. So conjugate base 2 is less stabilised through resonance, Lastly water is least acidic than above depicted compounds.