18. Predict the products from reaction with NaBH or LiAIH' then Hao. (10 pts.) OH CH3
Predict the (stable organic) products NaBH, CH,оH 1 2. HC, H,о NaBH, (1 eq.), сн,он 1. 2. HC, H,о NaBн(осн)» (1 еч.), сн,он 1. 2 HCI, H,о LIAIH (1 eq THF 1. Br 2. HC, H,о
Predict the products Predict the Product. Provide the stable organic product(s) for each reaction below NaBH CHOH 1 2 HCI, H,0 NaBH, (1 вg.)., сн,он 1. 2. HC, н,о 1. NaBH(осH (1 eq.), сн,он CI 2. HCI, H,O 1. LIAIH (1 eq.), THF Br 2. HCI, H2O
Question #2 Predict the products of the following reactions involving amines NH 1.) LiAIH, THF 2.) H, H2O NH CH 1.) CHI (excess) 2.) Ag20 3.) Heat (b)
**WRITTEN WORK** Draw the product of the following reaction. 1. Hg(OAc), H2O/THF 2. NaBH Y
Question 49 **WRITTEN WORK** Draw the product of the following reaction. 1. Hg(OAc), H,O/THF 2. NaBH, 2 = = =
3. Draw the organic product of the reduction of each of these carbonyl compounds using NaBH, in ethanol. 4. The reduction of this ketone with NaBHin ethanol give two organic products. Explain why there are two products and draw both of them in a way that clearly shows the difference.
organic chem lab questions 3&4 3. NaBH, usually reacts slowly or not at all with esters. Therefore, LiAlH, is often needed to reduce esters. Why do you think LiAlH, is more reactive than NaBH. (Hint: Compare the electronegativity of H versus Al or B). 93 4. Draw the mechanism for the following reaction using curved arrows. NaBHA CH, OH OH
NaNH Br liq. NH 1) BH3, THF 2) H202, NaOH 1)Hg (OAC)2 B 2, THF-H2O 2) NaBH B SOCI Structure A Structure B
IA] 1)-LAHTHE 2)-Hjo. IBI 1Bl Raney Ni /H Solvent) ICl NaBH, 0 Ethanol Solvent) 2-H0 NPh ?N