6. "Proton transfer with pK close to 4 "is correct option
Inflection point is point with highest slope and also an equivalence point. Hence,inflection at pH=4 means pka is 4 as all acid and base are neutralized and a proton transfer has been carried out.
7.Two histidine residue with somewhat different pka value act as acids and bases during catalysis.
In first step histidine-119 act as acid while histidine-12 act as base and form a 2'3'-cyclic intermediate which further reacts with water.
8. Cellulose and glycogen both are polysaccharides. Both have α-D Glucose as a subunit . Cellulose form plant cell wall, while glycogen helps in storage of glucose in animals
Hence, Above statement is true.
9. The active site contains an aspartic acid that must be Deprotanated and glutamic acid that must be protonated.
At pH less than 5 , glutamic acid ionises and cannot supply hydrogen ion
At pH above 5,aspartic acid gets protonated hence will not be able to stabilise the carbonium ion
Hence, Activitiy is highest at pH=5
Question 6 (1 point) in the A pH versus rate curve with an inflection point at...
My answers are:
Question 1: False
Question 4: proton transfer with a pK close to 4
Question 5: the active site contains an aspartic acid and
glutamic acid, both of which must be deprotonated
Question 8: 2 histidine residues with somewhat different pKa
values act as acids and bases during catalysis
Can someone please check my answers?
Question 1 (1 point) Cellulose and glycogen are both structural polysaccharides True False Question 4 (1 point) _ in the A pH versus...
The active site of lysozyme contains two amino acid residues essential for catalysis: Glu35 and Asp52. The pKa values of the carboxyl side chains of these residues are 5.9 and 4.5, respectively. What is the ionization state (protonated or deprotonated) of each residue at pH 5.2, the pH optimum of lysozyme? How can the ionization states of these residues explain the pH-activity profile of lysozyme.
24. The enzymatic activity of lysozyme is optimal at pH S.2 and decreases above and below this phH value. Lysozyme contains two amino acid residues in the active site essential for catalysis: Glu and Asp5?. The pK value for the carboxyl side chains of these two residues are 5.9 and 4.5, respectively. What is the ionization state of each residue at the pH optimum of lysozyme? (1 Pt) a. vcan the ionization states of these two amino acid residues explain...
Question 1 (1 point) Which of the following best describes glycogen? Question 3 (1 point) All the protease mechanisms we discussed in class involved formation of a covalent acyl enzyme intermediate. O Alinear polymer of glucose joined by a(1,6) linkages. True False O A polymer of glucose joined by a(1,4) linkages with a(1,6) linkages every 5-10 residues. Question 4 (1 point) O A polymer of glucose joined by B(1,4) linkages with a(1,6) linkages every 5-10 residues. In the mechanism of...
Question 1 (1 point) Which of the following best describes glycogen? Question 3 (1 point) All the protease mechanisms we discussed in class involved formation of a covalent acyl enzyme intermediate. O Alinear polymer of glucose joined by a(1,6) linkages. True False O A polymer of glucose joined by a(1,4) linkages with a(1,6) linkages every 5-10 residues. Question 4 (1 point) O A polymer of glucose joined by B(1,4) linkages with a(1,6) linkages every 5-10 residues. In the mechanism of...
Question 2. Draw the following mechanisms. You must clearly show all atoms and curly arrows. a. Draw the side chain of a histidine acting as a base to remove proton from water. Then the resulting hydroxide acts as a nucleophile to attack the carbonyl of the molecule acetone, forming a tetrahedral intermediate b. Draw a deprotonated serine attacking the carbon of a peptide bond, forming a covalent tetrahedral intermediate, then show the collapse of the tetrahedral intermediate and cleavage of...
what are the correct answers?
Question 4 (1 point) Saved How many equivalents of NaOH base would you expect to add to phosphoric acid when adjusting the pH to 6.82 ? Hint: pKa values are in the notes 0.5 1.5 2.5 o 1.0 2.0 Question 6 (1 point) Citric acid is a triprotic acid with three carboxylic acid groups having pK,values of 3.1,4.8, and 64. If a solution of citric acid has a predominantly means greater then 50% pH of...
(1) The following diagram represents a titration curve of histidine as pH increases; pKa = 1.82 represents the terminal carboxylic acid group. pK, represents the terminal amino group: 6.0 represents the R-group, and pK, E 9.17 7.59 pH 182 3.0 20 10 H (equivalents) At what point on the diagram is histidine predominantly present as the following species? COO A, at pH < 1.82 B. between pH 1.82 and pH 6.0 C) between pH 6.0 and pH 9.17 D. at...
1. A comic book villain is holding you at gun point and is making you drink a sample of acid. She gives you a beaker with 100ml of a strong acid with pH=5. She also gives you a beaker of a strong base with a pH=10. You can add as much of the strong base to the strong acid as you want, and you must then drink the solution. You'd be best off trying to make the solution neutral before...
1. Given the following peptide, which of the following
statements is true?
Question options:
a) The N-terminal residue is leucine.
b)This peptide contains 4 amino acid residues.
c) The peptide contains a total of 6 ionizable groups.
d) The net charge of this peptide at pH 7 is +1 Locate any
peptide bond along the backbone of the given peptide.
e) The bond between the C (of the C=O) and the N (of the N-H) of
a peptide bond has...