Explain how one duplication event of a chromosomal region will have the potential to be expanded...
Explain how one duplication event of a chromosomal region will have the potential to be expanded in future generations to many additional changes of the same region. Assume duplication mutant chromosomes can successfully go through meiosis with a homolog that has a different number of copies in the region of interest (i.e., meioses that occur in chromosomal heterozygotes).
Homework Answers
When the condition occurs sporadically, it is caused by a random error during the formation of the egg or sperm cell, or during the early days after fertilization. The duplication occurs when part of chromosome 1 is copied (duplicated) abnormally, resulting in the extra genetic material from the duplicated segment.
They are caused by nondisjunction, which occurs when pairs of homologous chromosomes or sister chromatids fail to separate during meiosis. The risk of nondisjunction increases with the age of the parents.
For many organisms, especially plants and fungi, changes in ploidy level between generations are major drivers of speciation. In mammals and birds, ploidy changes are typically fatal.
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