1. Give at least two examples where surface-active excipients can be used to improve therapeutic outcomes...

Question

Question

1. Give at least two examples where surface-active excipients can be used to improve therapeutic outcomes of a medication.

2. Give at least two examples of drugs that are incompatible with potassium metabisulfite (provide references)

Answer 1

Answer #1

1. Examples of Surface active excipients:

1. Ophthalmic excipients (in liquid form)-

· It has been observed that some ophthalmic drugs can be used as ophthalmic excipients.

· These ophthalmic excipients, when introduced as surface active agents an enhanced corneal permeation was observed.

2. Surface excipients in solid form:

· The drug may be incorporated with ad-mixture of surface active proteins, which helps in easy release and penetration.

· The surface active protein may be incorporated on the surface coating such as of capsules.

· One of the best applications is in case of suppositors.

Answer 2

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