Question

What series of events would be necessary for an activated hormone dimer complex to return to its inactive monomeric state?

Answer 1

Hormones are strong chemicals, which directly mix in the blood and then can be picked by the targeted cell for the further perusal of the specialized cell to maintain the homeostasis or integrity of the cell.

They act on a particular conformation suppose some hormones are functionally active at a dimer complex and this is an active stage of the hormone for further functioningto the cell. In the case of dimerization, hormones bind with the specific receptor with help of accessary molecules and form dimer complex and active transcription (activation of certain genes which are responsible for protein formation) and its monomer form is not an active form (inactive). Like EGF when dimerize with other protein can activate other signaling molecule inside the cell and later form is an inactive form.

Similarly in case of Tyrosine receptor protein is alone is inactive form when it binds with alpha helix of the membrane can induce several cellular signals inside a cell

Cortin protein pots phosphorylated due to protein kinass and become dimer and activate the pothway Depicerylation Dimer (Active) Monomer (inactive)