Question

Smallpox Incidence and Death in 18th centruy Boston, MA Cases of naturally acquired smallpox Cases of inoculated smallpox Death from smallpox — % of population The graphs in Figure 2 (right) tell the story of naturally-acquired and inoculated smallpox deaths in Boston in the 1700s. Consider the findings in the upper part of the graph in light of the findings shown in the lower part. State the overall conclusion to be drawn from the whole graph. Nowadays, when a new medicine or treatment or practice becomes available, government authorities ask three important questions: a) is the new treat ment safe, b) does the new treatment really work, and c) is the treatment practical and is it feasible to make and deliver the vaccine at a realistic cost? Data and graphs from all sorts of experiments on tissue samples and animals in the research lab, and from clinical trials on human volunteers is reported to panels of expert reviewers, who make recommendations to the arms of government that oversee research funding and medical oversight, like the Food and Drug Administration. % of population Question 5. Would Boylston's results in his 1721 clinical trial meet the three basic demands we make in modern clinical trials? 1721 1730 1752 1764 1776 1778 1779 Year of smallpox outbreak in Boston, MA Figure 2. Smallpox incidence and death in 18 century Boston, MA. Credit: Niederhuber, M. 2014. The fight over inoculation during the 1721 Boston smallpox epidemic. SITN Boston, Harvard University, CC BY-NC-SA 4.0. <http://sitn.hms.harvard.edu/flash/special-edition- on-infectious disease/2014/the-fight-over-inoculation-during-the- 1721-boston-smallpox-epidemic>.

answer question #5

use this to answer the question

Answer 1

Yes,it meet the modern clinical trial method.

1.the new treatment was safe because the inoculation was in natural way and also he was experienced in this work

2.it really work since the sick people number was reduced

3.yes,it was practical and feasible,by his publication work was spread through newspaper