Question

1. Why do cancer cells rely so much on metabolism of glucose ?

A. Because cancer cells grow in an anaerobic environment.

B. Because cancer cells display increased oxidative phosphorylation.

C. To regenerate NADH.

D. To synthesize small molecule building blocks and membranes required for cell growth.

E. Because cancer cells have decreased protein synthesis.

2. In general, which of the following sequential barriers to metastasis is the easiest to overcome for cancer cells ?

A. Vessel entry through acquisition of local invasiveness

B. Exit from the blood into a remote tissue or organ

C. Survival of cells in the foreign tissue

D. Initial growth of cells in the foreign tissue

E. Persistence of growth in the remote site

Answer 1

Answer molecule building blocks (1) To synthesize small and membranes required for cell growth. Explanation . Glycolysis provide most of the building blocks required for cell proliferation, Cancer cells (and normal proliferating cells). have been proposed to need to activate glycolysis, despite the presence of oxygen to prdiferate. Therefore, option to is correct answer.

(2.) Andwer- (B) Exit from the blood into a remote tissue or organ . Explanation - Metastasis steps includes & Separation from the primary tumor invasion through tissue around the initial lesion and penetration of their basement membranes entry into the blood vessels and survival within blood spread via blood vessels is Called hematogenous spread. Lymphatic spread is most common route of initial metastasis Hor Carcinomas. Exit from the blood into a remote tiesul or organ is a sequential Ibarriers to metastasis is the easiest to Lovercome for Cancer cells.