Question

3. In electron transfer, only the quinone portion of ubiquinone undergoes oxidation-reduction; the isoprenoid sidechain (R group, circled) remains unchanged. What is the function of this chain? CH CH30 CH,0 CH2-CH-C-CH20-H Ubiquinone (Q) CH (fully oxidized Semiquinone radical (QH) CH30 CM Hte h Ubiquinol (QH 2) (fully reduced) CH, O CH OCH

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Answer 1

The function of quinone of ubiquinone is to accept electrons from complex 1 and complex 2. Complex 1 gains electron after the oxidation of NADH and complex 2 gains electron after the oxidation of FADH2. Both of these complexes pass on their electrons to quinone of ubiquinone which gets reduced into ubiquinol. Than the electrons are passed on to complex 3. Thus ubiquinone is a mobile electron carrier located in the inner mitochondrial membrane and quinone is the main reaction centre of this molecule which accept and donate electrons.

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