Question
3. Plasma membrane is a selectively permeable membrane and it allow only limited substance to pass through freely but other substance require energy or carrier molecule to get transported. The different type of transport are:
I. Simple diffusion:
II. Fasciliated diffusion
III. Primary active transport
IV. Secondary active transport
Differences among various type of membrane transport are:
Simple diffusion | Fasciliated diffusion | Primary active transport | Secondary active transport | |
Movement of molecules | From higher concentration to lower concentration | From high concentration to lower concentration | From lower concentration to higher concentration | From lower to higher concentration |
Require energy | No | No | Yes | Yes |
Require transport proteins | No | Yes | Yes | Yes |
Require carrier protein | No | Yes | Yes | Yes |
There are mainly two type of transport protein. First is carrier protein and second is channel protein.
I. The channel protein mainly transport ions against the electrochemical gradient whereas carrier transport molecules.
II. The position of channel protein is fixed but confirmation of carrier protein change in plasma membrane.
III. Channel protein have high transporation rates as compare to cartier protein.
#3 2. Explain the synthesis of lipids at the ER membrane and how transmembrane proteins are...
What is Co-translational insertion of secreted and transmembrane proteins into the ER membrane including translocon, secreted proteins, type 1 transmembrane protein, type 2 transmembrane proteins?
associated with it. Use figure 5.1 as a guide to some of the components. 2. Explain the synthesis of lipids at the ER membrane and how transmembrane proteins are inserted. -- ----- -LStannat ud
How do single pass and multi-pass transmembrane proteins become inserted into a membrane?
#4 TICI CU. 3. Compare and contrast types of membrane transport including transport proteins. 4. Distinguish between exergonic/endergonic, anabolic/catabolic reduction/oxidation reactions.
Match the following: Integral (intrinsic) membrane proteins Transmembrane protein Porins C-- Lipid-linked proteins Peripheral (extrinsic) proteins 1. Channel-forming proteins found in the outer membranes of bacteria, with a beta-barrel motif. 2. Proteins that are associated with membranes, but can be dissociated by relatively mild procedures. 3. Proteins that completely span the membrane. 4. A general class of proteins that are tightly bound to membranes by hydrophobic interactions. 5. Membrane-associated proteins that have covalently-bonded lipids.
The plasma membrane is composed of both lipids and proteins. The relative concentration of each in the plasma membrane is partly regulated by the A. chromosomes, which dictate the types and number of membrane molecules that are generated B. Golgi complex, which functions in sorting molecules destined for the membrane C. rough endoplasmic reticulum, which functions in the translation of mRNA into membrane proteins D. vacuoles, which transport molecules to the plasma membrane
Explain the transport of extracellular membrane proteins following their post translational modification in the ER.
1. Final modification of proteins and lipids Golgi body lov Ribosomes 2. Control of substances moving into and out of cell. Rough ER 3. Translate the messages in mRNA into proteins. Nucleolus 4. Proteins made here are often exported out of the cell. Plasma membrane < 5. Site of vesicle formation and synthesis of lipids occurs here. Smooth ER 6. Assemble ribosomal (rRNA) subunits.
Is every isotonic solution isosmotic? Explain and provide an example. Many membrane proteins contain transmembrane segments (ie segments which penetrate through the membrane). How must these proteins be formed to allow them to act as an ionic channel? What specialisation would you need to allow it to function as a voltage-gated channel? If sodium is a smaller ion than potassium, then how can a channel be specific for potassium (ie. does not also allow sodium through)?
1. Describe how proteins are targeted and synthesized in the ER. 2. Describe nuclear pore transport. Why a pore and not a simple membrane translocator? 3. Describe how exocytose and endocytose vesicle targeting mechanisms.