Question

13. In the Kingdom of Utopia the King's oldest son has blue eyes (B), a strong jaw (S) and dimples (D) all of which segregate as dominant mendelian factors. His 999 wives have brown eyes (b), weak jaws (s) and undimpled cheeks (d) and each of them produces one child for him. The son is delighted to find that just one son of his 999 children has blue eyes, strong jaws and dimples like him, because he has a deep love of genetics and therefore understands this outcome. To help the son explain this outcome to his kind but, not so bright father A) state the phase of the alleles in the son and B) draw the genetic map for these three factors indicating the correct gene order and the genetic distance in centimorgans (CM) using Morgan's mapping function C) Calculate the coefficient of interference for these three genes. (16 points) Child's phenotype Frequency blue eyes, weak jaw, dimples 40 brown eyes, strong jaw, dimples 255 brown eyes, strong jaw, no dimples | 34 brown eyes, weak jaw, dimples 201 Child's phenotype Frequency blue eyes, strong jaw, dimples 1 blue eyes, strong jaw, no dimples | 193 blue eyes, weak jaw, no dimples 270 brown eyes, weak jaw, no dimples 15

draw please

Answer 1

Solution is given below:

Solution: 13. Given Blue eyes (B) Strong jaw (s) / dominant diniples (1) J Parts ... brown eyes (b) 7 weak jaw (3) Recessive ne dimples (d) _ I traits. T Type parentallinen 40 SCO- (single cross over) Parental I child's phenotype frequency I genotype blue eyes, weak jau, dinebles y 4o BPD brown eyes, strong jang | 255 / 6SD 1 dimples as I brown, strong, no cembley brown, weak, bsd dimples blue eyes, strong, dimples 85) 34 SCO-I SCO- (Double (yessover) 1. BSd SCO-T 270 Bod blue, strong, - no dimples blue, weak, no L no dimples brow, weak, no no ciuples Parental Inod 5 bod l Dco. Parcuts ajo pa A Gametes :- Bb So Dd x Bb Sa Dd yes & strong jaw, dimples) - BSD Blue, strong, Dimples d - Bsd - Blue strong, dimples BT - BoD - Blue weak, dimples Bsd Blue weak, no draples - bSD Brown strong, dimples - bsd Brouon strong, no diuples b&D - Brown Weat, druples bad Brown, weak, no dimples - 64 Whook method) A DAGADA bl. 2 bodo

A) Phase of alleles of son + B6 Ss Dd hong, Dimples) eyes B) for calculating gene iculating gene order and genetic distance! Gemitic distance = Reconebinahon frequency blow Huese goues g befineen agenes kecombination frequency 3C0 blw a genes + DCO 100 IX 100 bl๖ ๕344 Total progeny. So X100 gew 300-T + DCO 700 201 + 193+15 999 999 genetic distance blive S&B (jaw and eye genes) - 400 y 100 - 40.0TIM = 494 = frequency = 0.40 DCO 0 genetic distance Y100 40.34 +1+5 999 8 0. 999 SCO -I 999 - blue BAD. X100 a frequency = 0.08 Parental ? etto 360 Ő B Gene order = [5, 6, D.

Coefficient of Luterferance = '- coefficient of coincidence- (0) given. Number of observed Dco dea served (coincidence Coeff.) Number of expected Deo No. of expected DCO = Expected Dco frequency x Total no. of progeny Expected Dco frequency = 'frequency of SCO-5 x Frequency of SCO-IL = 0.40 X0.08 -0.32 i No. of expected Dco = 0.32 x 999 ACES - = 0.1875 32 Hence, E -1 0 .1875 ( coeff. cf Interference) = 10.8125] Ans