There is a class of NAD-dependent deacetylases that are thought to play a role in the response to nutritional status.
(A) Histones are the substrates for some of these deacetylase enzymes. How would you expect deacetylation of histones to affect transcriptional activity of genes that reflect nutritional status?
(B) One specific member of this class of enzymes activates acetyl-CoA synthetase. How might deacetylation activate acetyl-CoA synthetase? Why would this reflect nutritional status? As a reminder, acetyl-CoA synthetase catalyzes the following reaction:
acetate + CoA + ATP → acetyl-CoA + AMP + PPi
A)Histone acetylation plays a major role in gene regulation.
It remove acetyl group and provides positive charge in Histone tail.
It affects the DNA structure and preventing from transcriptions.it also affects signal transduction in living system.
b)role of acetyl coA synthetase is forming the new chemical bond between the molecules.
It plays important role in synthesis of fatty acids and involved in TCA cycle.
There is a class of NAD-dependent deacetylases that are thought to play a role in the...
1. According to the paper, what does lactate dehydrogenase (LDH) do and what does it allow to happen within the myofiber? (5 points) 2. According to the paper, what is the major disadvantage of relying on glycolysis during high-intensity exercise? (5 points) 3. Using Figure 1 in the paper, briefly describe the different sources of ATP production at 50% versus 90% AND explain whether you believe this depiction of ATP production applies to a Type IIX myofiber in a human....