Question

Catastrophe LL Disassembly Microtubule length (um) Rescue embly Time (min) The graph above shows the process of Dynamic Instability by measuring microtubule length over time. Microtubules undergoing assembly (Blue lines) have: OT-form tubulin capping the minus end. A mix of T and D form tubulin at the plus end. OD-form tubulin capping the minus end. OT-form tubulin capping the Plus end. OD-form tubulin capping the Plus end.

Answer 1

Assembly and disassembly of microtubules is an active process in the cell cytoskeleton. Assembly involves the polymerization or rescue phase, in which new units are added to the length of microtubules. On the other hand, disassembly involves removal of tubulin units from the microtubule structure, which tends to shorten it's length.

Assembly involves rescue whereas disassembly involves catastrophe.

During assembly, alpha and beta forms of tubulin, which are GTP bound are added from the plus end of microtubule.

Hence, correct choice should be:

(d) T form tubulin capping the plus end.

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