Question

1. You are presenting with advanced flu-like symptoms (i.e., cough, fatigue, fever, and malaise) and visit the doctor. The doctor rules out an influenza infection and tells you to drink lots of fluids and get plenty of bed rest. Should you insist on being tested for coronavirus infections? Why or why not? 2. Last year you endured the flu and multiple viral infections. Will this help protect you from further virus infections? If so, to what extent? 3. Scientists are still studying the immune response to infection with the coronavirus. Propose what the innate immune response and the adaptive immune response may be like using information we've previously learned in class and lab. (minimum 4 sentences) 4. Describe one major signaling pathway that may be involved with the response to infection with coronavirus. (minimum 5 sentences) 5. A relative returns home from an area recently afflicted with an outbreak of the coronavirus. What symptoms should they be wary of in the case of infection? What symptoms pose the threat of a more serious version of the virus?

Answer 1

Yes, one Coronavirus Tes; one should insist on being dested for Tonavirus infection. His because all the symptoms cough, cold, fever and malaise match with Tonavirus positive cases. No; Virus infection for cold, cough brythu virus does not protect you from next bear infections becouse fue virus change it component en form and our body can not remember or lack amy memory cell regarding viral mitection trinate immune response will be first line , defence against Viral infection before adaptive immune response activate.'Hence it will recruits Ammune cells (T& B cells) to site of infection through brodaction of chemical factors a med, stors toke Cytokines . Adaptive immune Tesponse occur when viral injechen out bom innste immune response and io mobilized Axecht immune regbmse C1577 anfibocły, lymbialytes -humoral cell medické response respectivelin 4 'A major signalling pathway activated by novel Coronavirus s ER Stress response. In resbare to ER stress stgnaling bathway of the unfolded prolein Tesbonse (UPR) are achiyake. > Disturbance ER homeostalis may occer under various pro logical or bathological pathway TUPR mediated by three ER dranime mbone Sensor amoly PKR-Like ER sein B ase (PERS), inositor requiring protein 1(RED) and activating transur stron al factor 6 (ATF6). SUPR faciliated adaptation to ER stress by reversible translation Menuation cause enhance m ER brotein folding capacith and activation of ERassociate degradation -CERADI. A 6 Symptoms shoula they be wam of clifficulties in taking breath, headache, cough Cold, high fever, soreness in throat etc. Symptoms of difficulties in taking breach show defect in lang function is more serious fymptoms y all. : 16 Diagonististro test prefer to run O Molecular dest to diagnost MERS-Gv alle ELISA! 0 RT-PCR ofrerese transcriptors Sample ONA Blood testy.