Question

QUESTION 5 A series of glucocorticoid receptor (GR) CDNA or its mutants linked to B-Galactosidase (Gal) were transfected into cells and tre dexamethasone. B-Galactosidase was assayed in the nucleus and cytoplasm of cells. B-Galactosidase activity was found in the transfectants containing the following: O GR CDNA-bGal O GR ligand binding domain-bal O GR DNA binding domain-bGal O GR activation domain-bGal O GR flexible domain-bGal O A and B OC,D,E O A, B, C, and D all of the above

Answer 1

A,B,C and D

glucocorticoid receptor domains such as ligand binding domain DNA bindind domin and activation domain may have beta galactosidase activity