Question

Reven ASO specific oligonucleotideprobes and the regions of the game in Ost Mercan Autosomal n doder. Swaliferent in Md. Al point mutton in the CFTA A G A cyathos Ten the most common muut A and B) Are whown on the diagram below. The inb e genare which they tryndze 5 penale underwont AS eating for cystiebrogla using a tour of the arabe shown above. The results of this test and shown below. Which individuals have only the wild tye son in the nions of both murtadan A And mutation B? Sen Al the recru Mutation CFTR Gene -Probel wild type -Probe 2 mutant - Probe 3 wild type Prok t ant 00000 000 Arcken 0000 Submi Previour Answer Request Angwe * Incorrect; Try Again: one attempt remaining Part B Which individual del mely e stic libri? Select all the corred Submit Request Answer <Route Assignment Provide Fowback

Answer 1

1)Individual 2 is wild type. Probe 1 and probe 3 binds with wild type sequences and wild type individuals should bind with only proble 1 and probe 3 but not the other 2 mutant probes. Individual 2 shows binding with probe 1,3 alone and it is wild type

2. Individual 4 will definitely have disease since they find with probes 2,4 and only one binding with wild type probe