Question

Which of the following aspects of the cell cycle would be most disrupted by cytochalasin B, a drug that binds to actin monomers and prevents them from polymerizing into filaments?
	Cell elongation during anaphase. Spindle attachment to kinetochores. DNA synthesis. Spindle formation. Cytokinesis.

Answer 1

The aspect of the cell cycle that would be most disrupted by cytochalasin B is- cytokinesis.

Cytochalasin B is a drug that prevents the formation of microfilaments and thus it disrupts the process of cytokinesis. In animal cells, the formation of cleavage furrow takes place when the contraction of a ring of microfilaments occurs. This contraction of microfilaments causes the division of parent cell into daughter cells. This is how cytokinesis occurs. But, cytochalasin B disrupts the formation of microfilaments and thus no cytokinesis take place.