Question

How is HPV able to keep its genome so small? a. oncogenic transformation b. overlapping reading...

How is HPV able to keep its genome so small?

a.

oncogenic transformation

b.

overlapping reading frames

c.

antigenic shift

d.

HPV does not have a small genome.

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Answer #1

Option b-Overlapping Reading Frames

Overlapping Reading frames is the presence of Start codons in different reading frames generate different polypeptides from the same DNA sequence.

The typical HPV genome contains six open reading frames (ORFs) encoding the structural proteins (L1 and. L2), proteins that mediate the viral life cycle .Hence with the help of Overlapping reading Frames HPV can generate different polypeptides from Same DNA Sequence and is able to keep its genome so small.


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