Question

1. Circle the stronger nucleophile and rationalize your choice H2S a. NaSH VS b. NaOH Н.О NH3 (compare all 4 species) KNH2 Vs Vs. Vs. с. CН-0 (In methanol) CH3O (in DMSO) vs d. Ethoxide (CH2CH2O tert-butoxide [(CH3)3O Vs. е. НО- Cl Vs.

Answer 1

ca Mas H > 1725 compared to Neutral nucleophiles, negatively charged species are acts as stronger Nucleophiles. Wash Negatively charged Nucleophice H-S-H Nash is Neutral Nucleoplice Mug good nucleophile Kan Has. ♡ KN H2 > Nach > NH3 > Heo . In a period from left to Right Nucleophilicity Decreases. C No F. pour NUMEO Philic cente, "center The sot NH3 SH 2 O good poor Nuryeoplice nucleoffice Good pucreoflinic

(c) Hoc-oo (in re thanol) ve Hzc & (in Duss) TH₂C-o in Drso is good lucked Phile than Helsin Methanol # onso polar aprotic solvent Methanol is polar protic solent. Nucleophilicity Increases in polar a protic Solvents. H₃C- CHEO > H3-C00 (H3 a (d) CHO . Ethoxide In go butoxice crowding Increases nucleophilicity Decreases, é o wtoxide is poor Nucleophile. But acts as stron one Ion acts as good. Nucleophile Ion acts as - Ethoxide (e) HD sco Hel Hot co ongacid weak conjugate base (Porr Nucleophile biza 2 HO + weak sentral strenger base(good Nucleophile)