Question

V. (20 points) Complete the reaction scheme. Complete structures are required; if a reagent has a common abbreviation, then the abbreviation can be used but must be completely correct. Sequential steps should be numbered. Include stereochemistry as appropriate. 5a. Predict the product. No stereochemistry needs to be shown 1) LDA (2 eq) H30+ Heat 3) H2O+ 5b. How many stereoisomers of the product would be formed? 5d. Predict the product. 5c. Predict the product. K2CO3 + CO2 + HOCH2CH3 5

Answer 1

Hol in A) LOA 59 Hol P 1) LOA - 2eg. thot beat 3) Hoo 5b There will be a chiral cephe now f * we have an isomers 4 isomers Holi 15003 CH Coz + CO2 tho CH CH3 Step 1 l equivalent of LDA will react with and Lanother with Less hindered proton & then react with ® to get 5b Step 2 - decorboxylationis in acel acidic condition gives product 5 step-Reaction with Chy I with K2CO3 gires se