Question

No 3, please determine to synthesize below the picture (include how to get retrosynthesize )

Possible Retrosynthesis of Amine TM - M 2 Q a . . . + logical disconnection leads to reasonable starting materials Nu amine TM No Starting maten als Synthesize of following TM using readily available starting materias 3) reagents ph Ny TM Jawaban Retrosintesis no.1. Refrosintesis NOTE ΤΜ “Ο ether

Answer 1

for q. no. 3:

1. we can disconnect from benzyl position, because this position is more reactive towards substitution (resonance stabilized) takes place readily and rest part will be primary amine hence synthetic eq. will be benzyl bromide and 2-methyl butanamine.

Given Ny » Hy = NH₂ - Reaction Năx + N + 7 , + H x Ciren Target molecule from Ph-ch} NH- 1. We can disconnect bond & will H synthons 11 Ph-cth Br benzyl bromide PherBr + IN Y Reaction 2-methyl butanamine Ph-CBNH X Tom

ext :- SONG Propyl haline sodium salt of phenol Reaction path > ųC CH CH Br ANO t propyl phenyl ethe