Question

2. Assign Ror Sfor each chirality center in the following molecules 3 point OF Is the compound b chiral or achiral? Explain (4 points) Chiral 3. Which one of the following hydrogens is the most reactive when the compound reacts with Bry/hu? Pick your answer and explain. (4 points) А в р WCH, H нсен 4. A secondary hydrogen is indicated at which position in the structure above? (2 points)

Answer 1

solution: CH3 R- configuration. CH2F R configuration H ot Br R configuration CH2F Horizon at Horizontal line - above the plane Vertical line - below the plane CH₂F CH₂ F 1800 Br H rotation L Br plane и- of - Вт .....k -..t - Br symmetry. Сн, F CH₂F Rotation of compound through 180° gives plane of symmetos. :: compound 6 is achiral.

③ BD Al I CH3 I HJ LH Brglhu / It u The hydrogen is most reactive when compound reacts with Bradhr because there is formation of 3 radicale : Radical stability order is 3 y 2o y to nr hr 23r -- Br + Br 3 radical more stable. CH3 - Primary hydrogen Tertiary hydrogen H H ) Secondary hydrogen