Question

1. Which of the following antibiotics would be considered "broad spectrum?"

   	A.	erythromycin
   	B.	isoniazid
   	C.	penicillin
   	D.	all of the above
   	E.	none of the above

2. Which of the following is FALSE?

   	A.	The most dangerous pathogens would require BSL-1.
   	B.	Physical controls are the usual choice for disinfection, antisepsis, and preservation.
   	C.	There are many antibacterial drugs because there are so many differences between pro- and eukaryotic cells.
   	D.	Once viruses complete the Entry phase, they cannot be harmed by antibodies or antivirals.
   	E.	Both A and B are false.

3. The cooperative activity of drugs is known as

   	A.	chemotherapy.
   	B.	synergism.
   	C.	antimetabolism.
   	D.	selective toxicity.
   	E.	cross resistance.

4. Methicillin is an example of the beta-lactam class of drugs that

   	A.	inhibits protein synthesis.
   	B.	inhibits cell wall synthesis.
   	C.	disrupts cytoplasmic membranes.
   	D.	inhibits nucleic acid synthesis.
   	E.	inhibits metabolic pathways.

5. Technically, a true antibiotic

   		is synthesized in laboratories.
   		is produced by yeasts.
   		is produced by a living organism.
   		is produced by bacteriophages.
   		is produced by eukaryotic organisms.

Answer 1

Q 1. Ans- A

Explanation- Erythromycin is a broad spectrum antibiotic that inhibits protein synthesis by binding to 23s rRNA and block the exit of peptide chain. Whereas isoniazid is a narrow spectrum antibiotic that targets mycobacteria only and penicilin is also a narrow spectrum antibiotic which inhibits cell wall biosynthesis.

Q 2. Ans- A) The most dangerous pathogens would require BSL-1.

Explanation- The most dangerous pathogen must require BSL-4 whereas BSL-1 is the first level.Disinfection can be done by Physical control.

Q 3. Ans- B) Synergism

Explanation- when two drugs interacts the total activity of them will be greater than the sum of individual effect of each drug. This is known as synergism.

Q 4. Ans- A) inhibits cell wall synthesis

Explanation- Methicilin belongs to the beta lactam group of antibiotic inhibits penicilin binding protein (PBPs) which are involved in peptidoglycan biosynthesis. Peptidoglycan is the main part of bacterial cell wall.

Q 5. Ans- E) is produced by eukaryotic organisms.

Explanation- the first true antibiotic penicilin was produced by Penicillium notatum which is a eukaryote